Inorganic Nanorods Enable the Memorization of Photoinduced Microlens Arrays in Dye-Doped Liquid Crystals.

The photoinduced molecular reorientation of liquid crystals (LCs) caused by their nonlinear optical responses has attracted much attention due to their large refractive index change, leading to promising applications in optical devices. This reorientation is typically induced by light irradiation above a threshold intensity and is temporary, with the initial orientation recovering unless the LCs are polymerized and cross-linked. Our report highlights the memory effect of molecular reorientation in LCs.

Cefazolin-induced hemolytic anemia in septic arthritis: A case report.

A 50-year-old woman living with untreated HIV and injection drug use presented with right shoulder pain. The shoulder exam and computed tomography (CT) scan were concerning for septic arthritis. She was started on empiric vancomycin and cefepime and underwent right shoulder debridement and humeral head resection.

Bending creep behaviour of various polymer films analysed by surface strain measurement.

Understanding the temporal bending deformation of polymer films is key to designing mechanically durable flexible electronic devices. However, such creep behaviour under persistent bending remains unclear due to a lack of precise and accurate bending strain analysis methods. Herein, we quantitatively analysed the bending creep behaviour of various polymeric films using our developed strain measurement method that can precisely measure surface strain from optical diffraction.

Optimal management of severe mpox in patients with uncontrolled human immunodeficiency virus.

In May 2022, a cluster of nontravel-related cases of human mpox were reported in the United Kingdom. The outbreak has since spread worldwide infecting over 85 000 patients and causing over 100 deaths. Recent data clearly suggest that patients infected with human immunodeficiency virus (HIV) with CD4 counts less than 200 cells per mm suffer significantly worse outcomes than immunocompetent patients.

Synthesis and Characterization of Side-Chain Liquid-Crystalline Block Copolymers Containing Cyano-Terminated Phenyl Benzoate Moieties.

Block copolymers, known for their capacity to undergo microphase separation, spontaneously yield various periodic nanostructures. These precisely controlled nanostructures have attracted considerable interest due to their potential applications in microfabrication templates, conducting films, filter membranes, and other areas. However, it is crucial to acknowledge that microphase-separated structures typically exhibit random alignment, making alignment control a pivotal factor in functional material development.

Tick-Borne Encephalitis: An Update for the Special Operations Forces Provider.

Tick-borne encephalitis (TBE) is a severe disease caused by the tick-borne encephalitis virus (TBEV). TBEV is endemic throughout Eurasia and can cause persistent neurologic deficits and death. Special Operations Forces (SOF) participating in field exercises or operations in TBE-endemic countries are at significantly increased risk of infection.

The Relationship between LRP6 and Wnt/β-Catenin Pathway in Colorectal and Esophageal Cancer.

High expression of low-density lipoprotein receptor-related protein 6 (LRP6), a key component of the Wnt/β-catenin signaling pathway, is reported to be associated with malignant potential in some solid tumors including breast cancer and hepatocellular carcinoma. Few reports, however, have examined its function and clinical significance in colorectal cancers (CRC) demonstrating constitutive activation of Wnt signaling. Here, we compared the expression level and function of LRP6 in CRC with that of esophageal squamous cell carcinoma (ESCC) bearing few Wnt/β-catenin pathway mutations.

Bilateral Above the Knee Amputation in Afghanistan.

Prolonged Casualty Care (PCC) has become an essential component to Special Operations Forces (SOF) pre-mission training. However, it has not regularly been required in recent combat operations with the availability of medical evacuation (MEDEVAC) support. Poor weather conditions at an austere SOF outpost created an emergency unreachable by aeromedical evacuation.

Crimean-Congo Hemorrhagic Fever: A Refresher and Update for the SOF Provider.

Crimean-Congo Hemorrhagic Fever (CCHF) is the most widespread tickborne virus causing human disease. CCHF wields a mortality rate up to 30% and was responsible for the death of a US Soldier in 2009. The virus is spread by the Hyalomma species of hard tick found across Central Europe, the Middle East, Africa, and Asia south of the 50° parallel.

COVID-19 Vaccines-All You Want to Know.

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has led to an unprecedented public health crisis. The collective global response has led to production of multiple safe and effective vaccines utilizing novel platforms to combat the virus that have propelled the field of vaccinology forward. Significant challenges to universal vaccine effectiveness remain, including immune evasion by SARS-CoV-2 variants, waning of immune response, inadequate knowledge of correlates of protection, and dosing in special populations.

Alignment Control of Smectic Layer Structures in Liquid-Crystalline Polymers by Photopolymerization with Scanned Slit Light.

Photoalignment control of hierarchical structures is a key process to enhance the properties of optical and mechanical materials. We developed an in situ molecular alignment method, where photopolymerization with the scanned slit light causes molecular flow, leading to two-dimensional precise alignment of molecules over large areas; however, the alignment control has been explored only on a molecular scale. In this study, we demonstrate this photopolymerization-induced molecular flow, enabling mesoscopic alignment of smectic layer structures composed of anisotropic molecules.

Smallpox as a Bioagent: A Refresher and Update for the SOF Provider.

Smallpox plagued humans for millennia until its eradication in 1980 following a successful global campaign led by the World Health Organization (WHO). It is the first known biological weapon to be used in war and has been weaponized in the past by the former Soviet Union. To date, smallpox remains a Category A Bioagent and is assessed to be a relevant threat to US military personnel.

Overview of COVID-19-Associated Invasive Fungal Infection.

Purpose Of Review: Invasive fungal infections are a complication of COVID-19 disease. This article reviews literature characterizing invasive fungal infections associated with COVID-19.

Recent Findings: Multiple invasive fungal infections including aspergillosis, candidiasis, pneumocystosis, other non- molds, and endemic fungi have been reported in patients with COVID-19.

Effect of Host Structure on Optical Freedericksz Transition in Dye-Doped Liquid Crystals.

The optical Freedericksz transition (OFT) can reversibly control the molecular orientation of liquid crystals (LCs) only by light irradiation, leading to the development of all-optical devices, such as smart windows. In particular, oligothiophene-doped LCs show the highly sensitive OFT due to the interaction between dyes and an optical-electric field. However, the sensitivity is still low for the application to optical devices.

Clinical impact of a metagenomic microbial plasma cell-free DNA next-generation sequencing assay on treatment decisions: a single-center retrospective study.

Background: Metagenomic next-generation sequencing of microbial cell-free DNA (mcfDNA) allows for non-invasive pathogen detection from plasma. However, there is little data describing the optimal role for this assay in real-world clinical decision making.

Methods: We performed a single-center retrospective cohort study of adult patients for whom a mcfDNA (Karius©) test was sent between May 2019 and February 2021.

Liquid crystalline 2D borophene oxide for inorganic optical devices.

Borophene has been recently proposed as a next-generation two-dimensional material with promising electronic and optical properties. However, its instability has thus far limited its large-scale applications. Here, we investigate a liquid-state borophene analogue with an ordered layer structure derived from two-dimensional borophene oxide.

Latent TB Infection in USSOF: A Refresher and Update.

Tuberculosis (TB) causes approximately 2 million deaths annually worldwide, with 2 billion persons estimated to be actively infected with TB. While rates of active TB disease in the US military are low, military service in TB-endemic countries remains an uncommon, but important source of infection. United States Special Operations Forces (USSOF) and enablers often operate in TB-endemic countries and, as an inherent risk of their mission sets, are more likely to have high-risk exposure to TB disease.

Novel Bending Sensor Based on a Solution-Processed CuO Film with High Resolution Covering a Wide Curvature Range.

A CuO film is prepared on a flexible polyethylene terephthalate substrate for a bending sensor using the spin-spray method, a facile and low-environmental-load solution process. The CuO bending sensor shows high sensitivity and high resolution not only over a wide range of curvatures (0 < κ < 0.21 mm) but also for very small curvature changes (Δκ = ∼ 0.

Effect of Crosslinkers on Optical and Mechanical Behavior of Chiral Nematic Liquid Crystal Elastomers.

Chiral nematic (N*) liquid crystal elastomers (LCEs) are suitable for fabricating stimuli-responsive materials. As crosslinkers considerably affect the N*LCE network, we investigated the effects of crosslinking units on the physical properties of N*LCEs. The N*LCEs were synthesized with different types of crosslinkers, and the relationship between the N*LC polymeric system and the crosslinking unit was investigated.

Photohardenable Pressure-Sensitive Adhesives using Poly(methyl methacrylate) containing Liquid Crystal Plasticizers.

Hardenable pressure-sensitive adhesives, which show pressure-sensitive adhesion state with weak adhesion strength in their initial semisolid state and general adhesion state with strong adhesion strength in their hardened state, are desirable in various industrial fields to improve efficiency of manufacturing and recycling products. Here we developed novel photohardenable pressure-sensitive adhesives triggered by photoplasticization of poly(methyl methacrylate) containing photoresponsive liquid crystal (nematic and smectic E) plasticizers at various ratios. It was found that photoplasticization, which is the photoinduced reduction of glass transition temperature and hardness of polymers, could be repeatedly induced by alternate irradiation with ultraviolet (UV) and visible (Vis) light in all mixtures, regardless of the phase structures of the photoresponsive plasticizers.