Publications by authors named "Shisen Yang"

Article Synopsis
  • Rutin is a flavonoid with potential benefits for treating Alzheimer's, preventing brain damage, and combating glioblastoma, but its therapeutic use is hindered by poor solubility and limited ability to cross the blood-brain barrier (BBB).
  • A new delivery system called transferrin-modified Rutin liposomes (Tf-Rutin-Lip) was developed to enhance Rutin's bioavailability and brain-targeting efficiency by incorporating transferrin into liposomes.
  • Experimental results showed that Tf-Rutin-Lip liposomes can cross the BBB without damaging brain cells, demonstrating improved pharmacokinetic properties compared to standard Rutin, thus highlighting their potential as a therapeutic strategy.
View Article and Find Full Text PDF

() is a critical disease affecting broiler health, with as its primary pathogen. compound extract (PHCE), formulated based on traditional Chinese veterinary principles, contains primarily flavonoids with antibacterial, anti-inflammatory, and antioxidant properties. However, PHCE's efficacy against -induced and its underlying mechanism remain unclear.

View Article and Find Full Text PDF