Publications by authors named "Shirshak Shrestha"

Transcranial ultrasound stimulation (TUS) is an emerging non-invasive neuromodulation technique capable of manipulating both cortical and subcortical structures with high precision. Conducting experiments involving humans necessitates careful planning of acoustic and thermal simulations. This planning is essential to adjust for bone interference with the ultrasound beam's shape and trajectory and to ensure TUS parameters meet safety requirements.

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Article Synopsis
  • Non-invasive brain stimulation techniques, like Transcranial Ultrasound Stimulation (TUS), have potential for brain plasticity but need more research for effectiveness in neurological treatments.
  • This study aimed to assess how different pulse repetition frequencies (PRF) of TUS affect motor corticospinal excitability in healthy participants.
  • Results showed that TUS at PRFs of 10 Hz and 100 Hz significantly decreased motor evoked potentials, suggesting PRF selection is crucial for TUS's application in reducing corticospinal excitability.
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