Publications by authors named "Shiro Setoyama"
Vascular endothelial growth factor (VEGF) has been noted in the pathogenesis of atherosclerosis. To examine the usefulness of the serum concentration of VEGF as an index of atherosclerosis, we analyzed the serum VEGF concentrations in 443 adults who underwent a medical checkup. The mean serum VEGF concentration of men (229+/-147 pg/ml) was significantly higher than that of women (182+/-112 pg/ml).
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- The study investigates the link between the R353Q polymorphism in the Factor VII gene and the occurrence of premature myocardial infarction (MI) in young Japanese men.
- In a sample of 127 MI patients under 45 years and 150 matched healthy controls, the Q allele showed a negative association with premature MI, suggesting it may offer some protective effects.
- While plasma levels of activated Factor VII (FVIIa) were higher in patients compared to controls, the difference was not statistically significant, but gene polymorphism did affect FVIIa concentrations significantly.
Recently, oscillometric devices have been developed that can measure blood pressure in the extremities and analyze pulse volume record. On the basis of the extremity pulse volume record, these devices can automatically determine three types of simply measured pulse wave velocity (PWV) (brachial PWV: heart to right upper arm; R-PWV: right upper arm-right ankle; and L-PWV: right upper arm-left ankle). The percent mean pulse volume record (%MPVR=the height that bisects the area of the pulse volume record/pulse pressure X100), a quantitative index of right brachial pulse volume record, can also be determined.
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