Pretreatment With P2Y Inhibitors in ST-Segment Elevation Myocardial Infarction: Insights From the Bern-PCI Registry.

Background: Evidence to support immediate P2Y inhibitor loading in ST-segment elevation myocardial infarction (STEMI) is limited.

Objectives: This study sought to compare outcomes of STEMI patients receiving immediate or delayed P2Y inhibitor treatment.

Methods: Using data from the prospective Bern-PCI registry between 2016 and 2020, we stratified STEMI patients undergoing percutaneous coronary intervention according to time periods with different institutional recommendations regarding P2Y inhibitor pretreatment.