Publications by authors named "Shirley Triche"
Article Synopsis
- The study compared deep brain stimulation (DBS) lead placement techniques for Parkinson disease patients, focusing on intraoperative MRI (iMRI) guidance versus microelectrode recording (MER) guidance to assess accuracy, safety, and motor outcomes.
- Researchers found that while both methods had similar complication rates (about 6-9%), iMRI guidance resulted in better lead placement accuracy (0.84 mm vs. 1.94 mm).
- Clinical outcomes indicated that patients who had iMRI-guided DBS experienced greater improvements in motor function than those with MER guidance, showcasing the potential effectiveness of iMRI in treatment plans.
Temporal profile of improvement of tardive dystonia after globus pallidus deep brain stimulation.
Parkinsonism Relat Disord
February 2015
Background: Several case reports and small series have indicated that tardive dystonia is responsive to globus pallidus deep brain stimulation. Whether different subtypes or distributions of tardive dystonia are associated with different outcomes remains unknown.
Methods: We assessed the outcomes and temporal profile of improvement of eight tardive dystonia patients who underwent globus pallidus deep brain stimulation over the past six years through record review.
Globus pallidus deep brain stimulation for adult-onset axial dystonia.
Parkinsonism Relat Disord
November 2014
Introduction: Generalized dystonia, both primary and secondary forms, and axial dystonias such as tardive dystonia, and idiopathic cervical dystonia are responsive to globus pallidus interna (GPi) DBS. There is a paucity of investigations probing the impact of DBS on adult-onset axial dystonia. We assessed the efficacy of GPi DBS in four patients with rare adult-onset axial dystonia.
View Article and Find Full Text PDFBackground: A role for vitamin D deficiency in Parkinson disease (PD) has recently been proposed.
Objective: To compare the prevalence of vitamin D deficiency in a research database cohort of patients with PD with the prevalence in age-matched healthy controls and patients with Alzheimer disease (AD).
Design: Survey study and blinded comparison of plasma 25-hydroxyvitamin D (25[OH]D) concentrations of stored samples in a clinical research database at Emory University School of Medicine.
Thirty-six patients with Parkinson's disease (PD) were randomized to either medical therapy (N = 18) or unilateral GPi pallidotomy (N = 18). The primary outcome variable was the change in total Unified Parkinson's Disease Rating Scale (UPDRS) score at 6 months. Secondary outcome variables included subscores and individual parkinsonian symptoms as determined from the UPDRS.
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