Team science competencies for clinical research professionals: A multileveled Delphi approach.

Background: The knowledge, skills, and abilities needed for clinical research professionals (CRPs) are described in the Joint Task Force (JTF) for Clinical Trial Competencies Framework as a basis for leveled educational programs, training curricula, and certification. There is a paucity of literature addressing team science competencies tailored to CRPs. Gaps in training, research, and education can restrict their capability to effectively contribute to team science.

Academic medical center clinical research professional workforce: Part 2 - Issues in staff onboarding and professional development.

Background: Defining key barriers to the development of a well-trained clinical research professional (CRP) workforce is an essential first step in identifying solutions for successful CRP onboarding, training, and competency development, which will enhance quality across the clinical and translational research enterprise. This study aimed to summarize barriers and best practices at academic medical centers related to effective CRP onboarding, training, professional development, identify challenges with the assessment of and mentoring for CRP competency growth, and describe opportunities to improve training and professionalization for the CRP career pathway.

Materials/methods: Qualitative data from a series of Un-Meeting breakout sessions and open-text survey questions were analyzed to explore the complex issues involved when developing high-quality onboarding and continuing education opportunities for CRPs at academic medical centers.

Psychosis in public mental health: Provider perspectives on clinical relationships and barriers to the improvement of services.

Whereas a growing literature has sought to understand challenges involved in the dissemination and implementation of specific evidence-based practices (EBP), few studies have centered on the perspectives of front-line community providers regarding best practices, clinical ideals and barriers to quality improvement for clients with psychosis. The goal of this project was to lay a foundation for future work aimed at improving the overall quality and impact of the multifaceted services typically provided to adults with psychosis served by the public mental health system. The findings reported here draw on a series of in-depth interviews and focus groups with 34 clinicians based at multiple inner-city community mental health sites.

Maximal aerobic capacity and the oxygen uptake efficiency slope as predictors of large artery stiffness in apparently healthy subjects.

Purpose: Large artery stiffness is now recognized as an important marker of cardiovascular health. The purpose of the present investigation was to assess the relationship between large artery stiffness and the oxygen uptake efficiency slope (OUES) and to determine whether the OUES is a viable surrogate for maximal oxygen uptake (VO(2max)) in a multivariate regression analysis developed to estimate large artery stiffness.

Methods: Two hundred seventy-five apparently healthy subjects (149 men; age = 48.

Association of hypertensive diastolic blood pressure with dyslipidemia during exercise in apparently healthy subjects.

Introduction: Diastolic blood pressure (DBP), which is influenced by cardiac output and total peripheral resistance, normally remains stable or decreases during the transition from rest to exercise. Dyslipidemia has been shown to attenuate vasodilation, and may therefore impede the normal reduction in peripheral vascular resistance during exercise. This investigation examines differences in lipid levels between apparently healthy individuals with a normal and hypertensive DBP response to exercise.

The relationship between C-reactive protein and other cardiovascular risk factors in men and women.

Introduction: C-reactive protein (CRP) has emerged as an important indicator of risk for cardiovascular disease. The impact of gender on the relationship between CRP and other cardiovascular risk factors, however, has not been thoroughly investigated.

Methods: Ninety men and 75 women participated in this study.