Comparison of the efficacy of micropulse diode laser transscleral cyclophotocoagulation using different energy protocols.

Purpose: This study aimed to explore the safety and efficacy of laser treatment settings of micropulse transscleral cyclophotocoagulation treatment in glaucoma patients and to evaluate the relationship between intraocular pressure (IOP) reduction and different treatment parameters.

Materials And Methods: A total of 74 eyes in 64 glaucoma patients with IOP over 21 mmHg or under 20 mmHg with visual field progression who underwent micropulse transscleral cyclophotocoagulation treatment were included. Patients were divided into success and failure groups based on criteria of 20% IOP reduction rate.

Correlation between structural progression in glaucoma and obstructive sleep apnea.

Background/objectives: To investigate the correlation between obstructive sleep apnea (OSA) severity and the structural and functional progression in patients with glaucoma.

Subjects/methods: This retrospective comparative cohort study included subjects from the polysomnography database in Chang Gung Memorial Hospital between June 1, 2009, and June 1, 2017, by identifying patients who had received diagnoses of primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), or glaucoma suspect. Patients with follow-up time of <3 years and/or <3 consecutive reliable optical coherence tomography (OCT) or visual field (VF) tests were excluded.

Anterior Chamber Angle and Anterior Segment Structure of Eyes in Children With Early Stages of Retinopathy of Prematurity.

Purpose: To compare structural differences in the anterior chamber angle (ACA) and related optic components in children with or without retinopathy of prematurity (ROP).

Design: Prospective cross-sectional study.

Methods: Setting: A referred medical center in Taiwan.

Regional Relationship between Macular Retinal Thickness and Corresponding Central Visual Field Sensitivity in Glaucoma Patients.

. To investigate the relationship between macular retinal thickness (MRT) and central visual field sensitivity (VFS) in patients with glaucoma. .

A method to preserve limbus during penetrating keratoplasty for a case of presumed PHACES syndrome with sclerocornea: A case report.

Background: Sclerocornea, a congenital corneal pathology characterized by bilateral scleralization of the cornea, which can be found in few cases with posterior fossa malformationshemangiomas-arterial anomalies-cardiac defects-eye abnormalities-sternal cleft and supraumbilical raphe (PHACES) syndrome. Presence of vascularization in peripheral cornea and smaller diameter of recipient cornea correlate to poor outcome of penetrating keratoplasty (PKP) in sclerocornea. Here we report a method to preserve limbus during PKP for small, irregular, and scleralized cornea.

The relationship of bleb morphology and the outcome of needle revision with 5-fluorouracil in failing filtering bleb.

To investigate the risk factors for failure of needling revision with 5-fluorouracil (5-FU) and to identify the correlation of outcomes of needling revision and the morphological features of dysfunctional filtration blebs using Moorfields bleb grading system.This retrospective, nonrandomized, comparative case-control study included 41 consecutive patients (41 eyes) who underwent 5-FU needling revision for failed or failing filtration blebs between July 2012 and August 2014 in Chang Gung Memorial Hospital, a referral center in Taiwan. The main outcome measures were the bleb survival and the correlation factors of bleb morphology before revision.

Anterior chamber depth and angle-closure glaucoma after central retinal vein occlusion.

Background: The purpose of this study was to report the anterior chamber (AC) depth and the attack of angle-closure glaucoma (ACG) in eyes with the recent onset of central retinal vein occlusion (CRVO).

Methods: This retrospective case series included 24 patients with recent onset of CRVO (within one month of attack) from July 2001 to December 2002. The mean follow-up period of the patients was 46 months (range: 3 to 92 months).

Acute angle-closure glaucoma in retinopathy of prematurity following pupil dilation.

Background: Pupil dilation is a known risk factor for acute angle-closure glaucoma. Regular retinal evaluation is necessary for retinopathy of prematurity (ROP) cases. An acute attack of angle-closure glaucoma following pupil dilation in regressed ROP has never been reported.

Neovascular glaucoma after central retinal vein occlusion in pre-existing glaucoma.

Background: To determine the outcome of central retinal vein occlusion (CRVO) in pre-existing glaucoma and the predisposing factors of developing neovascular glaucoma (NVG).

Methods: We retrospectively assessed a pre-existing glaucoma CRVO group and a non-glaucoma CRVO group to elucidate the demographics, clinical course and ocular parameters of these two cohorts. Among the pre-existing glaucoma cases, the predisposing factors for the development of NVG were monitored, including the retinal capillary non-perfusion status, intraocular pressure (IOP) and best-corrected visual acuity (BCVA) at presentation.

Epithelial phenotype in total sclerocornea.

Purpose: To understand whether the epithelial phenotype in total sclerocornea is corneal or conjunctival in origin.

Methods: Four cases of total sclerocornea (male:female = 1:3; mean age = 5.4 ± 4.

The validity of clinical feature profiles for cytomegaloviral anterior segment infection.

Background: Anterior segment cytomegalovirus (CMV) infection, which can be presented as anterior uveitis and corneal endotheliitis, has recently been reported in immunocompetent patients. We would like to access the validity of two presumed characteristic clinical profiles: profile 1, non-herpes simplex virus (HSV)/varicella zoster virus (VZV) corticosteroid-recalcitrant inflammatory ocular hypertensive syndrome (IOHS), and profile 2, corneal endotheliitis with specific coin-shaped keratic precipitates (KPs), that could be helpful in identifying CMV anterior segment intraocular infection.

Methods: Patients with either profile 1 or profile 2 or both were enrolled consecutively from the uveitis service in Chang Gung Memorial Hospital, Taoyuan, between January 1, 2006 and May 31, 2010.

Intravitreal loading injection of ganciclovir with or without adjunctive oral valganciclovir for cytomegalovirus anterior uveitis.

Background: A pilot study was conducted to evaluate the therapeutic results of intravitreal ganciclovir injection as a loading dose with or without the following oral valganciclovir for the treatment of cytomegalovirus (CMV) anterior uveitis in immunocompetent patients.

Methods: Six consecutive patients in whom active CMV anterior uveitis was detected by polymerase chain reaction assay of the aqueous humor were enrolled between January 2006 and December 2008. These patients received an intravitreal injection of ganciclovir (2 mg/0.

Glaucoma is associated with peripheral vascular endothelial dysfunction.

Purpose: To evaluate peripheral vascular endothelial function in patients with normal-tension glaucoma (NTG) and primary open-angle glaucoma (POAG) using noninvasive endothelium-dependent flow-mediated vasodilation (FMD).

Design: Case-control study.

Participants: Thirty patients with NTG, 30 with POAG, and 30 healthy age- and gender-matched controls.

Systemic high-sensitivity C-reactive protein levels in normal-tension glaucoma and primary open-angle glaucoma.

Purpose: To determine the systemic high-sensitivity C-reactive protein (hsCRP) level in patients with normal tension glaucoma (NTG) and primary open-angle glaucoma (POAG).

Materials And Methods: With the exclusion of patients with cardiovascular and other systemic diseases, 40 patients with NTG, 40 with POAG, and 40 normal controls were enrolled in this study. Each patient underwent blood sampling for hsCRP, biochemistry, and lipid profile analysis.

Contact diode laser transscleral cyclophotocoagulation for refractory glaucoma: comparison of two treatment protocols.

Background: Diode laser transscleral cyclophotocoagulation has shown promising results in the treatment of refractory glaucoma. Treatment with a lower energy level per pulse and lower total energy is safer but may be less effective. We performed a study to evaluate the clinical effectiveness and safety of contact transscleral cyclophotocoagulation using two different protocols in the treatment of Chinese patients with refractory glaucoma.

Secondary pigmentary glaucoma associated with piggyback intraocular lens implantation.

A 51 year-old man developed bilateral pigmentary glaucoma with uncontrolled intraocular pressure (IOP) and signs of pigmentary dispersion syndrome after piggyback intraocular lens (IOL) implantation. Cataract surgery had been performed with in-the-bag implantation of poly(methyl methacrylate) IOLs in both eyes. Increasing myopia was subsequently corrected with implantation of an AcrySofIOL (Alcon Laboratories) in the ciliary sulcus of each eye.

Spontaneous, late, in-the-bag intraocular lens subluxation in a patient with a previous acute angle-closure glaucoma attack.

Cataract surgery was performed in a 49-year-old woman 16 months after an acute angle-closure glaucoma attack. Zonular dialysis was observed during surgery, but the intraocular lens (IOL) was implanted in the capsular bag uneventfully. At 4 1/2 months, 1 IOL loop wrapped in the bag herniated into the anterior chamber.

Comparison of standard white-on-white automated perimetry and short-wavelength automated perimetry in early glaucoma patients.

Background: To evaluate the relationship between short-wavelength automated perimetry (SWAP) and the standard white-on-white automated perimetry (W-W) in detection of early glaucomatous visual field deficits.

Methods: Twenty-four patients suspected of having glaucoma and who had experience with automated visual field tests were evaluated by SWAP and standard W-W perimetry. Results of the mean deviation (MD), pattern standard deviation (PSD), pattern deviation probability plot, test reliability, and test time were compared.