CTGF, FN1, IL-6, THBS1, and WISP1 genes and PI3K-Akt signaling pathway as prognostic and therapeutic targets in gastric cancer identified by gene network modeling.

Objective: Gastric cancer (GC) is one of the most common malignancies worldwide and it is considered the fourth most common cause of cancer death. This study aimed to find critical genes/pathways in GC pathogenesis to be used as biomarkers or therapeutic targets.

Methods: Differentially expressed genes were explored between human gastric cancerous and noncancerous tissues, and Gene Ontology and Kyoto Encyclopedia of Genes and Genomes signaling pathway enrichment analyses were done.

Head-to-head comparison of commercial artificial intelligence solutions for detection of large vessel occlusion at a comprehensive stroke center.

Purpose: Despite the availability of commercial artificial intelligence (AI) tools for large vessel occlusion (LVO) detection, there is paucity of data comparing traditional machine learning and deep learning solutions in a real-world setting. The purpose of this study is to compare and validate the performance of two AI-based tools (RAPID LVO and CINA LVO) for LVO detection.

Materials And Methods: This was a retrospective, single center study performed at a comprehensive stroke center from December 2020 to June 2021.

Diffusion-Based Molecular Communication Channel in Presence of a Probabilistic Absorber: Single Receptor Model and Congestion Analysis.

In this paper, a diffusion-based molecular communication channel is modeled in presence of a probabilistic absorber. The probabilistic absorber is an absorber which absorbs molecules upon collision with probability q . With random walk analysis, the discrete probability function of particle location in the presence of a probabilistic absorber can be found.

Lifetime Improvement of a Multiple Transmitter Local Drug Delivery System Based on Diffusive Molecular Communication.

In this paper, a multiple transmitter local drug delivery system associated with encapsulated drug transmitters is investigated. One of the limitations of drug delivery systems is the reservoir capacity. In order to improve the lifetime of drug transmitting nanomachines, and, hence, the longevity of drug delivery scenario, the system is associated with encapsulated drug transmitters.