A Canadian Survey on Adverse Symptoms Experienced by Solid Organ Transplant Recipients.

Introduction: Adverse symptoms experienced by solid organ transplant recipients remain largely unexplored despite their purported frequency.

Objective: To characterize patient perspectives on adverse symptoms, identifying the most problematic symptoms and the perceived cause and treatability, and to evaluate their impact on quality of life (QoL) and medication adherence.

Methods: An electronic survey was distributed to members of the Canadian Transplant Association, to characterize perceptions on symptom experience (Modified Transplant Symptom Occurrence and Distress Scale), and QoL (Short Form-12), medication adherence (Basel Assessment of Adherence to Immunosuppressive Medications Scale), demographics, and clinical situation.

Impact of the SIMPL-SYNC Refill Synchronization Program on medication adherence: A pragmatic randomized controlled trial.

Objective: To determine the impact of the SIMPL-SYNC refill synchronization (SSRS) service compared with that of usual care (UC) on medication adherence when applied as an opt-out strategy among patients receiving chronic medications.

Design: This was a pragmatic randomized controlled trial.

Setting And Participants: The study was conducted in 2 community pharmacies located in Saskatchewan, Canada.