Selenium Biofortification Impacts the Tomato Fruit Metabolome and Transcriptional Profile at Ripening.

In the present work, the effects of enriching tomatoes with selenium were studied in terms of physiological, metabolic, and molecular processes in the last stages of fruit development, particularly during ripening. A selenium concentration of 10 mg L with sodium selenate and selenium nanoparticles was used in the spray treatments on the whole plants. No significant effects of selenium enrichment were detected in terms of ethylene production or color changes in the ripening fruit.

Se-Enrichment Pattern, Composition, and Aroma Profile of Ripe Tomatoes after Sodium Selenate Foliar Spraying Performed at Different Plant Developmental Stages.

Foliar spray with selenium salts can be used to fortify tomatoes, but the results vary in relation to the Se concentration and the plant developmental stage. The effects of foliar spraying with sodium selenate at concentrations of 0, 1, and 1.5 mg Se L at flowering and fruit immature green stage on Se accumulation and quality traits of tomatoes at ripening were investigated.

[In-hospital outcomes of endarterectomy and coronary artery bypass grafting in multiple diffuse lesions of coronary arteries].

Background: According to a series of studies, performing coronary endarterectomy in direct myocardial revascularization increases the risk of myocardial infarction and in-hospital mortality. There are no commonly accepted indications for carrying out endarterectomy, and in clinical practice this technique is used in severe diffuse lesions of coronary arteries.

Aim: The study was aimed at assessing in-hospital clinical outcomes of coronary artery bypass grafting (CABG) with the use of endarterectomy in patients with severe multiple diffuse lesions of coronary arteries.

A dynamic human motion: coordination analysis.

This article is concerned with the generic structure of the motion coordination system resulting from the application of the method of virtual holonomic constraints (VHCs) to the problem of the generation and robust execution of a dynamic humanlike motion by a humanoid robot. The motion coordination developed using VHCs is based on a motion generator equation, which is a scalar nonlinear differential equation of second order. It can be considered equivalent in function to a central pattern generator in living organisms.

[Capacities of multidetector spiral computed tomography in the planning and postoperative examination of patients undergoing coronary artery bypass surgery].

Multiple investigations show that multidetector spiral computed tomography (MSCT) bypass grafting becomes an alternative to invasive coronary angiography in detecting coronary graft stenoses and occlusions. The investigation retrospectively estimated the patency of aortocoronary and mammary coronary artery anastomoses by MSCT bypass grafting. Examinations were made in 85 (326 anastomoses) patients who had undergone aortocoronary and mammary coronary artery bypass surgery and had MSCT bypass grafting within 3 years after the surgery.

Pair-wise multicomparison and OPLS analyses of cold-acclimation phases in Siberian spruce.

Analysis of metabolomics data often goes beyond the task of discovering biomarkers and can be aimed at recovering other important characteristics of observed metabolomic changes. In this paper we explore different methods to detect the presence of distinctive phases in seasonal-responsive changes of metabolomic patterns of Siberian spruce (Picea obovata) during cold acclimation occurred in the period from mid-August to January. Multivariate analysis, specifically orthogonal projection to latent structures discriminant analysis (OPLS-DA), identified time points where the metabolomic patterns underwent substantial modifications as a whole, revealing four distinctive phases during acclimation.

[Left main coronary artery stenosis and progression of coronary artery atherosclerosis after angioplasty and stenting in patients directed to coronary artery bypass surgery].

Recent investigations demonstrated appearance of left main coronary artery stenosis after PTCA. We performed a retrospective study of specific characteristics of development of coronary lesions after percutaneous coronary interventions (PCI) in patients subjected to coronary artery bypass grafting (CABG) because of angina recurrence after PCI. Data of 150 patients operated because of angina recurrence after PCI were analyzed.

[Long-term follow-up use of "cypher" sirolimus-eluting stents in patients with coronary heart disease after coronary artery bypass grafting with occlusive lesions of the coronary artery].

Unlabelled: The aim of this study is to assess the 1 and 2-year follow-up of treatment with Cypher drug- eluting stents (Cordis, Johnson & Johnson, USA) for chronic symptomatic coronary artery occlusions in CHD patients after coronary artery bypass graft. That was a retrospective study that included 51 patients who had been implanted Cypher stents. A control group comprised 65 symptomatic patients with coronary heart disease (CHD) after coronary artery bypass grafting with occlusive lesions of the coronary artery, who was carried out only conservative treatment (without PTCA).

Experience in early rehabilitation of patients after coronary artery bypass graft surgery.

Unlabelled: A strategy of rapid in-hospital postoperative rehabilitation is currently a priority trend in managing the patients after coronary artery bypass graft (CABG) surgery.

Objective: To investigate the baseline characteristics and peculiarities of perioperative treatment of patients with a short period ofin-hospital rehabilitation.

Materials And Methods: We studied a total of 690 patients who had endured CABG operations according to the conventional technique performed over the period from January 2007 to August 2008.

Experimental testing of a method for on-line identification of the cerebrospinal fluid system.

Accurate estimates of the compliance and out-flow resistance of the human cerebrospinal fluid system are important for diagnosis of a medical condition known as hydrocephalus. In this paper we present a system which provides simultaneous on-line estimates of the outflow resistance and compliance. It's performance is experimentally verified using the same apparatus used to perform actual patient diagnoses and a specially designed physical model of the human cerebrospinal fluid system.

Assessment of cerebrospinal fluid outflow conductance using an adaptive observer--experimental and clinical evaluation.

Idiopathic normal pressure hydrocephalus (INPH) patients have a disturbance in the dynamics of the cerebrospinal fluid (CSF) system. The outflow conductance, C, of the CSF system has been suggested to be prognostic for positive outcome after treatment with a CSF shunt. All current methods for estimation of C have drawbacks; these include lack of information on the accuracy and relatively long investigation times.

[Comparative analysis of efficacy of endovascular interventions in native vascular bed and grafts in patients with ischemic heart disease after coronary artery bypass surgery].

Aim: Investigation of efficacy of endovascular interventions in native vascular bed and grafts, elucidation of factors, affecting immediate and remote prognosis after endovascular treatment. MATERIAL AND METHODS Coronary stenting was carried out in 212 patients who had previously undergone coronary bypass surgery. Stents were implanted into native vessels and grafts in 116 (native vessels group) and 96 (grafts group) patients, respectively.

[Potentialities of non-invasive diagnosis of coronary artery anomalies by electron-beam tomography and multislice computed tomography].

Aim: To assess diagnostic value of electron-beam computed tomography and multislice computed tomography (EBT and MSCT) for diagnosis of congenital anomalies of coronary arteries (CA).

Material And Methods: Non-invasive coronary angiography with EBT and MSCT has been performed in 1162 patients.

Results: Different anomalies of coronary arteries have been found in 10 (0.

Association of lipoprotein(a) excess with early vein graft occlusions in middle-aged men undergoing coronary artery bypass surgery.

Objective: To assess the relationship of lipoprotein(a) to early vein graft occlusions in patients after coronary artery bypass grafting.

Methods: We studied 102 male patients (mean age 52.3 +/- 8.

[Results of endovascular revascularization with the use of stents after coronary bypass surgery in patients with ischemic heart disease].

Aim: To compare results of stenting in patients with and without prior coronary artery bypass grafting (CABG).

Methods: In 21 patients after CABG stents were implanted both in venous grafts and native vessels (secondary revascularization) and in 25 patients without history of CABG native vessels were stented (primary revascularization).

Results: Primary revascularization: there was 1 periprocedural non Q wave myocardial infarction (4%), angina disappeared in 88% and recurred in 1 year in 24% of patients; one year restenosis rate - 18.

[Role of electron-beam tomography in diagnosing patency of aortocoronary and mammary-coronary shunts (from data from a 3-year study)].

Aim: To assess informative value of electron-beam tomography (EBT) and to compare dynamics of occlusive defects of autovenous and autoarterial shunts.

Material And Methods: 36 patients with coronary heart disease entered the study. All the patients have undergone coronary artery bypass operation and/or mammarocoronary bypass operation (CABO and MCBO, respectively).

[Results of stenting and surgical treatment in patients with ischemic heart disease and multivessel coronary artery involvement].

Efficacy of surgical and endovascular (with the use of stents) methods of treatment was assessed in 56 patients with ischemic heart disease and double and triple vessel involvement. Coronary artery bypass grafting (CABG) was carried out in 31, implantation of stents - in 25 patients. Clinical factors used for assessment of efficacy of treatment were development of events (deaths, myocardial infarctions), presence of angina, changes of exercise capacity.

[Changes of autologous coronary vessels and aortocoronary grafts in patients with ischemic heart disease after coronary artery bypass grafting].

Aim: 1) to assess effect of coronary lesion morphology on changes of grafts during first year after surgery; 2) to study the state of native coronary vascular bed during first year after surgery; 3) to elucidate special features of atherosclerosis in grafts and coronary arteries in remote period after surgery.

Material And Methods: One hundred eighty seven patients with 3-vessel coronary artery disease subjected to aorto-coronary or mammary-coronary grafting.

Results And Conclusion: Proportions of closed venous grafts were 24,2% among grafts to arteries with 50-75% stenoses, 13.

[Minimally invasive coronary artery bypass surgery].

From 19.06.97 to 06.

Cardiopulmonary bypass and cell-saver technique in combined oncologic and cardiovascular surgery.

The purpose of this study was to work out an adequate operative technique for patients with malignant tumors who also need open heart surgery or procedures on major blood vessels. We had 8 such patients. In 6 of them, a tumor (3 cases hypernephroid cancer and 3 cases retroperitoneal sarcoma) had grown through the inferior vena cava (IVC) up to the right atrium.

[Prehospital care in traumatic shock].

Clinical investigations performed in 735 patients have shown that in addition to the improvement of organisation of the medical aid and the universally recognized resuscitation measures for trauma shock, the prophylactics and treatment of intoxication, metabolic, immune and other disorders developing in the patients soon after trauma should be started as early as at the prehospital step.