Publications by authors named "Shiri Avni"
Background: Currently, there is limited information on the level of apixaban in kidney transplant (KT) patients with atrial fibrillation and the influence of apixaban therapy on the level of immunosuppression and graft function.
Methods: This was a cross-sectional prospective study of 19 KT patients treated with apixaban. The levels of apixaban were measured using a chromogenic assay calibrated for apixaban and compared with those predicted by the manufacturer.
Article Synopsis
- * Researchers identified 17 new variants of the TRRAP gene in 24 patients, linking specific gene mutations to two clinical spectrums: one leads to multi-systemic syndromes with structural malformations and intellectual disabilities, while the other is associated with autism spectrum disorder and epilepsy.
- * Both clinical groups exhibited distinct facial features and showed altered gene expression related to neuronal function in skin fibroblasts, suggesting a strong genotype-phenotype correlation that can aid in clinical evaluations of TRRAP variants
Mild cognitive impairment (MCI) and healthy aging have been shown to be associated with mild parkinsonian signs (MPS). We performed a door-to-door observational and follow-up study amongst consenting residents of Wadi Ara Arab villages in northern Israel aged ≥65 years (n=687) to examine whether MPS represent a risk factor for MCI and/or conversion from MCI to Alzheimer's disease (AD). In Phase 1, 223 cognitively normal (CN) and 173 MCI subjects were assessed by interview for medical history, neurological examination, motor part of the Unified Parkinson Disease Rating Scale (mUPDRS) (divided into item-clusters: axial, limb bradykinesia, tremor and rigidity) and cognitive tests.
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