Publications by authors named "Shiref Kasem"

Article Synopsis
  • Colposcopy is a procedure used to evaluate the cervix in patients with abnormal Pap smears, playing a key role in early cervical cancer detection.
  • The study aimed to assess the efficacy of local anesthetics for pain relief during colposcopy-guided biopsies, analyzing data from 11 randomized clinical trials (RCTs) out of 1339 identified studies.
  • Results indicated that while local anesthetics increased pain during the speculum insertion, they significantly reduced pain during the biopsy itself; however, there’s insufficient evidence to firmly recommend their routine use in practice.
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Background: Bone metastasis is reported to be associated with poor quality of life, and increased risk of hospitalization. We aim to synthesize evidence from published randomized controlled trials (RCTs) which compared the efficacy of denosumab versus bisphosphonates in patients with advanced cancers.

Methods: We searched for all published RCTs in the following electronic databases: PubMed, Scopus, Web of Science, and Cochrane Central.

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