Prenatal ambient pesticide exposure and childhood retinoblastoma.

Background: Retinoblastoma is a rare tumor of the retina, most commonly found in young children. Due to the rarity of this childhood cancer, few studies have been able to examine prenatal pesticide exposure as a risk factor.

Objective: To examine the relationship between childhood retinoblastoma and prenatal exposure to pesticides through residential proximity to agricultural pesticide applications.

Residential proximity to pesticide application as a risk factor for childhood central nervous system tumors.

Background: Pesticide exposures have been examined previously as risk factors for childhood brain cancers, but few studies were able to assess risk from specific agents.

Objective: To evaluate risks for childhood central nervous system tumors associated with residential proximity to agricultural pesticide applications.

Methods: Using the California Cancer Registry, we identified cancer cases less than 6 years of age and frequency matched them by year of birth to 20 cancer-free controls identified from birth certificates.

A mixtures approach to solvent exposures and amyotrophic lateral sclerosis: a population-based study in Denmark.

Studies of occupational solvent exposures and amyotrophic lateral sclerosis (ALS) have been conflicting. We conducted a population-based case-control study of mixed occupational solvent exposures and ALS. Using the Danish National Patient Registry, we identified ALS cases in Denmark from 1982 to 2013, and matched them to 100 controls based on sex and birth year.