Publications by authors named "Shiran S Moore"
Emergent cesarean section during active labor-does cervical dilatation matter?
Arch Gynecol Obstet
December 2024
Purpose: To compare the immediate and late complications associated with emergent cesarean sections (CS) performed during the first and second stages of active labor.
Methods: We conducted a retrospective analysis of electronic medical records from a single academic center, including data from 577 patients who underwent emergent cesarean sections at 4 cm or more of cervical dilatation. Patients were divided into two groups: those who had CS during the first stage of labor (4-9 cm dilatation) and those who had CS at complete dilatation (10 cm).
Article Synopsis
- A study was conducted to explore how the severity of congenital diaphragmatic hernia (CDH) affects patients' perceptions of their quality of life (QOL).
- Researchers used the Pediatric Quality of Life Inventory (PedsQL) to gather data from patients aged 5 and older and found that those with severe CDH reported significantly lower QOL scores, especially in areas like physical activity and social interactions.
- The findings highlight the need for better health monitoring and improvements in care based on patient experiences, particularly for those with severe cases of CDH.
Article Synopsis
- The study aimed to identify specific fetal echocardiography markers that can accurately predict coarctation of the aorta (CoA) in newborns, as current diagnostic methods have a high rate of false positives.
- Researchers conducted a retrospective case-control study comparing various echocardiographic measurements of infants who required treatment for CoA after birth with those who did not, stratifying results based on gestational age (GA).
- Results showed that specific ratios of right to left ventricular dimensions and deformation parameters are the most effective predictors of true CoA, particularly the RV/LV end-diastolic area ratio, which identified all cases of CoA with a high sensitivity.
This review provides a comprehensive summary of the current understanding of pulmonary hypertension (PH) in congenital diaphragmatic hernia, outlining the underlying pathophysiologic mechanisms, methods for assessing PH severity, optimal management strategies, and prognostic implications.
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- - The study investigated how early cardiac function impacts outcomes like death and severe bronchopulmonary dysplasia (BPD) in extremely premature infants born before 29 weeks, through a retrospective analysis of 176 infants from 2015 to 2019.
- - Findings revealed that infants who experienced death/severe BPD had lower birth weights and showed reduced heart function on echocardiograms taken within 21 days, with specific measurements indicating worse cardiac performance and potential pulmonary issues.
- - The research concluded that diminished cardiac function early in life correlates with increased risks of severe BPD and related pulmonary hypertension, suggesting the importance of monitoring heart health in neonates and its potential role in predicting outcomes.
Article Synopsis
- Researchers studied the link between left cardiac 3D echocardiographic measurements and brain injury in newborns with neonatal encephalopathy in a single hospital.
- They found that on the second day of life, babies with brain injury had larger left ventricle end-diastolic volume and stroke volume compared to those without brain injury.
- Additionally, these infants showed a higher peak global circumferential strain on the 3D echocardiogram, suggesting possible cardiac changes associated with brain injury.
Article Synopsis
- The study investigated how the degree of prematurity (specifically the gestational age at birth) affects cardiac size and function in extremely preterm infants at near-term age.
- Researchers analyzed data from infants born at less than 29 weeks of gestational age, comparing those born before and after 26 weeks.
- Results showed that infants born before 26 weeks had significantly smaller left heart dimensions compared to their slightly more mature counterparts, highlighting potential long-term cardiac concerns.
Objective: This study aimed to evaluate the prevalence of adverse outcomes, specifically pulmonary hypertension (PH) and suspected or confirmed necrotizing enterocolitis (NEC), and their associated risk factors, in neonates treated with diazoxide.
Study Design: A retrospective study in infants born ≥ 31 weeks and admitted between January 2014 and June 2020. Combined adverse outcomes possibly associated to diazoxide were PH (systolic pulmonary pressure of ≥40 mm Hg or an eccentricity index ≥1.
Article Synopsis
- The study aimed to compare vascular flow trends in the anterior cerebral artery (ACA) of neonates with congenital heart defects (CHD), focusing on those with and without diastolic systemic steal during their first week of life.
- Researchers used Doppler ultrasound and echocardiography to analyze 38 neonates daily from day 1 to 7, categorizing them based on the presence of retrograde flow in the aorta.
- Results showed that while peak systolic and mean velocities increased over time regardless of retrograde status, those with retrograde flow experienced a significant decrease in ACA-end-diastolic velocity and increases in resistive and pulsatility indexes, indicating cerebrovascular steal in the first week of life.
Article Synopsis
- - Three preterm infants treated with paracetamol for significant patent ductus arteriosus (PDA) experienced acute hemolysis during their hospital stay, with no other causes identified.
- - These infants were all born within the same year, highlighting a potential concern regarding the side effects of paracetamol in this specific patient group.
- - The authors emphasize the need for increased awareness of this rare side effect, as the relationship between paracetamol and hemolysis in preterm infants remains unclear.
Article Synopsis
- * Using near-infrared spectroscopy, researchers measured regional oxygen saturation (rSOS) before and after each feeding method in 21 infants under 32 weeks gestation.
- * Results show that continuous feeding lowers rSOS compared to bolus feeding, but it does not significantly affect the oxygen extraction by the intestines; there was also a slight trend towards reduced systemic oxygen levels after bolus feeding.
Article Synopsis
- - The study aimed to understand the characteristics of vagal syncope in young children and see if they often undergo unnecessary diagnostic tests or get misdiagnosed.
- - Data was collected from children up to six years old who experienced sudden loss of consciousness, revealing that a significant number had a family history of syncope and identifiable triggers for their episodes.
- - Findings indicated that vagal syncope in young kids is similar to that in older ages, suggesting that quick recovery after a faint should lead to considering this diagnosis to prevent excessive testing and hospital stays.
Aim: Febrile urinary tract infections (UTIs) may be associated with long-term renal damage. Our goal was to identify risk factors for future UTIs in children who had voiding cystourethrography (VCUG) as a part of an antenatal hydronephrosis (ANH) assessment or after a febrile UTI.
Methods: We conducted a cohort study based on the medical records of children aged 0-24 months who underwent a VCUG between January 2004 and December 2011 and had at least six months of follow-up.