Publications by authors named "Shira M Siegel"
Neurobiol Aging
September 2024
Article Synopsis
- The hypothalamus plays a crucial role in maintaining homeostasis and is linked to aging, with changes observed in mouse models leading to cognitive decline.
- A study involving older adults used advanced imaging to explore the relationship between hypothalamic microstructure and neurocognitive factors, revealing that changes in mean diffusivity were age-related and correlated with decreased cortical thickness.
- The research found that lower levels of fractional anisotropy in the hypothalamus may predict cognitive decline over time, marking the first evidence of a direct link between hypothalamic structure and cognitive aging in humans.
