New-Onset Guttate Psoriasis: A Long-Term Follow-Up Study.

Background: Guttate psoriasis (GP), a distinct variant of psoriasis, is more common in children and adolescents. The long-term course of these patients has sparsely been examined, with few studies reporting the rates of relapse, persistence, and further development of the psoriasis vulgaris phenotype.

Objectives: The objective of this study was to characterize the long-term outcomes of new-onset GP and elucidate the potential factors associated with a persistent disease course.

Correcting for imaging gradients-related bias of T relaxation times at high-resolution MRI.

Purpose: High-resolution animal imaging is an integral part of preclinical drug development and the investigation of diseases' pathophysiology. Quantitative mapping of T relaxation times (qT ) is a valuable tool for both preclinical and research applications, providing high sensitivity to subtle tissue pathologies. High-resolution T mapping, however, suffers from severe underestimation of T values due to molecular diffusion.