The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired pneumonia patients with type 2 diabetes mellitus.

Background: The features of community-acquired pneumonia (CAP) patients with type 2 diabetes mellitus (T2DM) differ from those without. This study aims to spot a routinely tested parameter with discriminative, predictive and prognostic value to enhance CURB-65's prognostic accuracy in CAP patients with T2DM.

Methods: We retrospectively studied consecutive CAP patients from 2020 to 2021, comparing laboratory parameters between patients with and without T2DM.

Numerical simulation and theoretical study on the impact of wind-sand flow of high-speed trains in long tunnel space.

When high-speed trains (HST) run in enclosed spaces such as long tunnels, the thermal accumulation of their suspension devices is continuous and cannot be effectively dissipated. In addition, previous experiments or simulations for the heat dissipation of HST in tunnel spaces did not consider the impact of sand. To clarify the impact of HWS-LT on the heat accumulation of HST equipment cabin, this study used the CFD method to numerically simulate the impact of different wind-sand flow concentrations or no-sand wind on the cooling of equipment in the long tunnel space.

Finite element analysis and optimization of tractor gearbox body under various kinds of working conditions.

As the main component of the tractor gearbox, the box has the functions of shifting operation and carrying the cab, it also carries part of the framework function. If the strength, stiffness, or vibration characteristics of the box do not meet the allowable requirements, large vibration and noise may occur, and even there is the possibility of fracture in some limiting conditions. To solve this problem, according to the structural parameters of a gearbox, the three-dimensional model of the box was established by using the three-dimensional modeling software Creo.

The associations of high academic performance with childhood ametropia prevalence and myopia development in China.

Background: To assess associations of high academic performance with ametropia prevalence and myopia development in Chinese schoolchildren.

Methods: This multicohort observational study was performed in Guangdong, China. We first performed a cross-sectional cohort analysis of students in grades 1 to 9 from Yangjiang to evaluate the relationship between academic performance and refractive status on a yearly basis.

[The influence of high fluoride exposure in drinking water on endocrine hormone in female].

Objective: To explore the influence of water fluoride exposure on reproductive hormones in female.

Methods: Cross-sectional study was conducted in seven villages of a county in Henan province by using simple random sampling including high fluoride area, defluoridation project area and control area on April, 2011 based on the preliminary study results of fluoride concentration in drinking water. Women who were born and growth or lived in the village at least 5 years and aged 18-48 years old were recruited using cluster sampling.

[Effect of fluoride on the expression of StAR mRNA and P450scc mRNA in the progesterone synthesis of mouse Leydig tumor cells].

Objective: To observe the effect of sodium fluoride on the expression of steroidogenic acute regulatory protein (StAR) mRNA and cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc) mRNA in the testosterone synthesis of mouse Leydig tumor cells (mLTC-1). and to explore the molecular mechanisms of fluoride on reproductive injury.

Methods: Using mLTC-1 cells as a model, progesterone in the supernatant of cell culture medium was measured by RIA.