Slicing Network for Wide-Field Fluorescence Image Based on the Improved U-Net Model.

Fluorescence imaging stands as a pivotal component in biomedical research, requiring the elimination of out-of-focus background noise resulting from wide-field volumetric illumination of the whole field-of-view and scattering within thick biological tissues. Traditional methods struggle to effectively address varying degrees of defocusing in fluorescence images. This study introduces the utilization of upU-Net, 3D U-Net, and 3D upU-Net as defocusing networks tailored for 2D and 3D wide-field fluorescence images, yielding notable enhancements.

Combined transcriptome and widely targeted metabolome analysis reveals the potential mechanism of HupA biosynthesis and antioxidant activity in .

Introduction: is a traditional Chinese herb that has gained much attention for its production of Huperzine A (HupA). HupA has shown promise on treating Alzheimer's disease (AD). However, the biosynthetic pathway and molecular mechanism of HupA in are still not well understood.

[Application of PBL in Clinical Practice of Chinese Medicine in Western Medicine Colleges].

Objective To observe the application value of problem-based learning (PBL) in clinical practice of Chinese medicine (CM). Methods Totally 162 clinical undergraduates were randomly and equally assigned to the observation group (PBL group) and the control group [lecture-based learning (LBL) group], 81 in each group. Clinical practice was conducted in them.