Photodynamic antibacterial activity of oxidase-like nanozyme based on long-lived room-temperature phosphorescent carbon dots.

In this study, a novel long-lived room-temperature phosphorescent (RTP) carbon dots (P-CDs) with the properties of ultraviolet/visible (UV/Vis) light photoresponsive oxidase-like nanozyme were synthesized from diethylenetriaminepentaacetic acid and through a one-step hydrothermal method. P-CDs were used as a light-driven oxidative-like enzyme for antimicrobial studies. The results showed that under UV/Vis light irradiation, P-CDs could efficiently convert O into O, and the strong oxidizing property of O greatly enhanced the growth inhibition of P-CDs on Gram-positive Staphylococcus aureus (S.

Preparation of room-temperature phosphorescence-ratiometric fluorescence magnetic mesoporous imprinted microspheres and its application in detection of malachite green and tartrazine in multimatrix.

The photoluminescent properties of Mn-doped ZnS quantum dots were fully exploited, and room-temperature phosphorescence (RTP)-ratiometric fluorescence (RF) magnetic mesoporous molecularly imprinted polymers (PFMM-MIPs) were prepared by integrating molecular imprinting technology. RTP was used to detect malachite green (MG). The fluorescence at 420 nm and the peak at 590 nm in the fluorescence mode were used as the response reference signals respectively to detect tartrazine (TZ).

Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury.

Acute liver injury (ALI) has an elevated fatality rate due to untimely and ineffective treatment. Although, schisandrin B (SchB) has been extensively used to treat diverse liver diseases, its therapeutic efficacy on ALI was limited due to its high hydrophobicity. Palmitic acid-modified serum albumin (PSA) is not only an effective carrier for hydrophobic drugs, but also has a superb targeting effect via scavenger receptor-A (SR-A) on the M1 macrophages, which are potential therapeutic targets for ALI.

The emerging possibility of the use of geniposide in the treatment of cerebral diseases: a review.

With the advanced discoveries in the field of pathogenesis, a series of cerebral diseases, such as cerebral ischaemia, Alzheimer's disease, and depression, have been found to have multiple signalling targets in the microenvironment. Only a few existing agents have been shown to have curative effects due to this specific circumstance. In recent decades, active ingredients isolated from natural plants have been shown to be crucial for original drug development.

Effects and mechanism of microRNA‑218 against lung cancer.

Lung cancer is the most prevalent and observed type of cancer in Xuanwei County, Yunnan, South China. Lung cancer in this area is called Xuanwei lung cancer. However, its pathogenesis remains largely unknown.

Phosphorimetric determination of 4-nitrophenol using mesoporous molecular imprinting polymers containing manganese(II)-doped ZnS quantum dots.

Mesoporous molecularly imprinted polymers (MIPs) containing mangnanese-doped ZnS quantum dots (Mn-ZnS QDs) were prepared for specific recognition and detection of 4-nitrophenol (4-NP). The Mn-ZnS QDs display orange room-temperature phosphorescence with excitation/emission peaks at 295/590 nm and a decay time of 2.0 ms.