Altered auditory repetition suppression and MMNm in relation to cognitive tests in older adults.

Cognitive changes with aging have been connected to deficiency in early-stage cortical repetition suppression (RS) and mismatch negativity (MMN). Here, we intended to investigate age-associated alterations of auditory RS and MMN by using a roving standard paradigm, and examine their relations to cognitive performances. Twenty-two young and 22 elderly adults were recorded with a magnetoencephalography.

Age Effect on Automatic Inhibitory Function of the Somatosensory and Motor Cortex: An MEG Study.

Age-related deficiency in the top-down modulation of cognitive inhibition has been extensively documented, whereas the effects of age on a bottom-up or automatic operation of inhibitory function were less investigated. It is unknown that whether the older adults (OA)' reduced behavioral performance and neural responses are due to the insufficient bottom-up processes. Compared to behavioral assessments which have been widely used to examine the top-down control of response inhibition, electrophysiological recordings are more suitable to probe the early-stage processes of automatic inhibitory function.