Publications by authors named "Shintaro Fujita"
Article Synopsis
- This study investigates the use of the Prognostic Nutritional Index (PNI) in predicting overall survival for patients with soft tissue sarcomas, finding that higher PNI scores correlate with longer survival.
- Researchers analyzed data from 111 patients treated between 2006 and 2022, utilizing blood sample results to evaluate PNI alongside other nutritional and inflammatory markers.
- Results showed that the high PNI group had significantly better survival rates, confirming PNI as a strong independent prognostic factor compared to other variables like age and tumor stage.
Although synovial sarcoma is a relatively common soft tissue sarcoma, primary intra-articular cases are extremely rare. Herein, we report a case of primary intra-articular synovial sarcoma arising from the hip joint, that was initially treated with hip arthroscopy. A 42-year-old male presented with a history of pain in the left hip for 7 years.
View Article and Find Full Text PDFBackground: Serum tartrate-resistant acid phosphatase 5b is well known to be increased in giant cell tumors of bone. However, there are only a few studies that analyzed the association with tartrate-resistant acid phosphatase 5b expression in those patients. Therefore, we analyzed the characteristics of patients with giant cell tumors of bone and high tartrate-resistant acid phosphatase 5b expression.
View Article and Find Full Text PDFBackground: Active surveillance (AS) has been suggested for managing extra-abdominal desmoid fibromatosis (EADF), but a substantial percentage of such patients transitioned to invasive secondary treatments. The anti-keloid medication tranilast is frequently used in Japan but its effectiveness for EADF is not well understood.
Methods: We retrospectively analyzed the medical records of EADF patients treated with tranilast between January 2009 and March 2021.
Article Synopsis
- Venous thromboembolism (VTE) is a significant risk for patients with malignant tumors and orthopedic issues, particularly those undergoing surgery for musculoskeletal tumors, prompting this study to analyze its prevalence and risk factors.
- A review of 270 patient records revealed that VTE was present in 9.5% of cases, with age over 60 and tumors located in the lower limbs identified as key independent risk factors.
- The study established a D-dimer cutoff value of 1.53 µg/mL for diagnosing VTE, with high sensitivity and moderate specificity, although D-dimer levels alone didn't correlate with VTE risk in multivariate analysis.
The first asymmetric total synthesis of (-)-hippodamine has been accomplished via the concise construction of its azaphenalene core, which is featured by the 2,4,6-chiral piperidine synthesis based on one-pot asymmetric azaelectrocyclization in the partially activated substituent system and the subsequent intramolecular Mannich reaction.
View Article and Find Full Text PDF