Development of a prediction model for target positioning by using diaphragm waveforms extracted from CBCT projection images.

Purpose: To develop a prediction model (PM) for target positioning using diaphragm waveforms extracted from CBCT projection images.

Methods: Nineteen patients with lung cancer underwent orthogonal rotational kV x-ray imaging lasting 70 s. IR markers placed on their abdominal surfaces and an implanted gold marker located nearest to the tumor were considered as external surrogates and the target, respectively.