Antibodies to three mycobacterial antigens, Soviet tuberculin and ultrasound-treated Mycobacterium tuberculosis (H37Rv) and M. bovis (BCG) were detected by enzyme immunoassay in 90 patients with pulmonary tuberculosis and 75 normal subjects. Antibody detection rates and levels were found related to the form of tuberculous process.
View Article and Find Full Text PDFZh Mikrobiol Epidemiol Immunobiol
January 1991
The spectrum of antibody response to M. tuberculosis antigenic determinants H37Rv and M. bovis antigenic determinants BCG was studied in serum samples from 33 healthy donors and 31 patients with infiltrative pulmonary tuberculosis by the method of immunoblotting.
View Article and Find Full Text PDFThe authors relate the data on the importance of a biochemical analysis of the pleural fluid for the differential diagnosis of pleurisy and identification of the early signs of pleural fluid suppuration. For the purposes of the differential diagnosis between transudates and exudates measurements are made of the protein content and LDH activity in the pleural fluid. The exudate protein/serum protein and exudate LDH/serum LDH ratios are computed in necessary cases.
View Article and Find Full Text PDFActivities of NAD-glyconydrolase from erythrocytes, alkaline and acid phosphatases from neutrophiles and acid phosphatase from lymphocytes were studied in patients with pulmonary tuberculosis as well as in experimental animals. Distinct alterations in the activity of the enzymes studied were observed in blood cells of guinea pigs inoculated with tuberculosis. In patients with active pulmonary tuberculosis activities of acid and alkaline phosphatases were altered in leukocytes and the activity of NAD-glycohydrolase--in erythrocytes.
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