Network and Evolutionary Analysis of Human Epigenetic Regulators to Unravel Disease Associations.

We carried out a system-level analysis of epigenetic regulators (ERs) and detailed the protein-protein interaction (PPI) network characteristics of disease-associated ERs. We found that most diseases associated with ERs can be clustered into two large groups, cancer diseases and developmental diseases. ER genes formed a highly interconnected PPI subnetwork, indicating a high tendency to interact and agglomerate with one another.

Morphology of the lingual papillae of the bharal (Pseudois nayaur).

We examined the dorsal lingual surfaces of an adult bharal (Pseudois nayaur) by scanning electron microscopy. The filiform papillae of the lingual apex and body consisted of a main papilla and smaller secondary papillae. The filiform papilla of the lingual body was big as compared to that of the lingual apex.

An Over 90 dB Intra-Scene Single-Exposure Dynamic Range CMOS Image Sensor Using a 3.0 μm Triple-Gain Pixel Fabricated in a Standard BSI Process.

To respond to the high demand for high dynamic range imaging suitable for moving objects with few artifacts, we have developed a single-exposure dynamic range image sensor by introducing a triple-gain pixel and a low noise dual-gain readout circuit. The developed 3 μm pixel is capable of having three conversion gains. Introducing a new split-pinned photodiode structure, linear full well reaches 40 ke.