Porous media combustion has significant advantages of high thermal efficiency and low pollution emissions. However, the flow state in the porous media will affect the reaction rate. In order to increase the rate of chemical reactions, the fluid flow resistance in the porous media must be reduced.
View Article and Find Full Text PDFThis paper makes a comparative study on the normal diffusion flame (NDF) and inverse diffusion flame (IDF) characteristics of dimethyl ether (DME) in microgravitational spherical diffusion flame geometry by simulations with detailed fuel chemistry and a transport model. It is found that there always existed two combustion modes (i.e.
View Article and Find Full Text PDFFlame extinction is one of the most essential critical flame features in combustion because of its relevance to combustion safety, efficiency, and pollutant emissions. In this paper, detailed simulations were conducted to investigate the effect of H addition on dimethyl ether spherical diffusion flame in microgravitational condition, in terms of flame structure, flammability, and extinction mechanism. The mole fraction of H in the fuel mixture was varied from 0 to 15% by 5% in increment.
View Article and Find Full Text PDF1-Hydroxy-7-azabenzotriazole (HOAT) was explored experimental and theoretical computation methods as a corrosion inhibitor for mild steel in 1 M sulfuric acid. These data indicate that HOAT has good ability to suppress corrosion of the mild steel, with ideal agreement with between experimental and computational results. Besides, the electrochemical experiments show that HOAT is a mixed-type corrosion inhibitor for mild steel in 1 M HSO.
View Article and Find Full Text PDFThe anti-corrosion inhibition effect of itraconazole on copper (Cu) in 0.5 M H₂SO₄ is observed with variety of experimental methods, including electrochemical measurement, surface morphology analysis, and theoretical calculations. These experimental results all confirm that itraconazole exhibits excellent anti-corrosion performance in the certain temperatures range (298 K⁻313 K) for copper in sulfuric acid solution.
View Article and Find Full Text PDFThe synthesis and anti-inflammatory effects of certain pyrazolo[4,3-]quinoline derivatives ⁻ are described. The anti-inflammatory activities of these derivatives were evaluated by means of inhibiting nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264.7 cells.
View Article and Find Full Text PDFβ-Lapachone (β-LAPA), a natural product from the lapacho tree in South America, is a potential chemotherapeutic agent that exhibit a wide variety of pharmacological effects such as anti-virus, anti-parasitic, anti-cancer, and anti-inflammatory activities. In order to discover novel anti-inflammatory agents, we have synthesized a series of β-LAPA derivatives for evaluation. Among them, 4-(4-methoxyphenoxy)naphthalene-1,2-dione (6b) was found to be able to inhibit NO and TNF-α released in LPS-induced Raw 264.
View Article and Find Full Text PDFThis study describes the synthesis and anti-inflammatory effects of furo[3', 2':3,4]naphtho[1,2-d] imidazole derivatives. Among these furo[3', 2':3,4]naphtho[1,2-d]imidazole derivatives, 2-(4-methoxyphenyl)furo [3', 2':3,4]naphtho[1,2-d]imidazole (12) exhibited a strong inhibitory activity against LPS-induced PGE(2) production, with an IC(50) value of 47 nM. Compound 12 is then further examined for its inhibitory effects in the protein expression of COX-2 and microsomal prostaglandin E(2) synthase-1 (mPGES-1) in Raw 264.
View Article and Find Full Text PDFA number of 2,3-diarylquinoline derivatives were synthesized and evaluated for antiproliferative activities against the growth of six cancer cell lines including human hepatocellular carcinoma (Hep G2 and Hep 3B), non-small cell lung cancer (A549 and H1299), and breast cancer (MCF-7 and MDA-MB-231) cell lines. The preliminary results indicated that 6-fluoro-2,3-bis{4-[2-(piperidin-1-yl)ethoxy]phenyl}quinoline (16b) was one of the most active compounds against the growth of Hep 3B, H1299, and MDA-MB-231 with a GI(50) value of 0.71, 1.
View Article and Find Full Text PDFCertain iminonaphtho[2,3-b]furan derivatives were synthesized from their respective carbonyl precursors in the regiospecific and the stereospecific manners. These compounds were evaluated for their antiproliferative effects against four human carcinoma cells (MCF7, NCI-H460, SF-268, and K562) and the normal fibroblast cell line (Detroit 551). Among them, (Z)-4-(hydroxyimino)naphtho[2,3-b]furan-9(4H)-one (8) and (Z)-4-methoxy-iminonaphtho[2,3-b]furan-9(4H)-one (9) exhibited GI(50) values of 0.
View Article and Find Full Text PDF