Publications by authors named "Shin-ichi Shirai"
Article Synopsis
- Acquired von Willebrand syndrome (AVWS) is linked to cardiovascular diseases like mitral regurgitation (MR), leading to a decrease in large von Willebrand factor (VWF) multimers, but its specifics with MR are still not fully understood.
- A study analyzed 84 patients with moderate to severe MR, finding that 69% exhibited a significant loss of VWF large multimers, especially in degenerative MR cases, but levels improved after mitral valve intervention.
- The findings indicate that while MR is commonly associated with loss of VWF large multimers, the overall risk of gastrointestinal bleeding remains low, and hemoglobin levels tend to stay stable post-treatment.
Rapid induction and maintaining a target temperature of 32.0-36.0°C within a narrow range for <24 hours are essential, but those are very hard to perform in postcardiac arrest syndrome (PCAS) patients.
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