Publications by authors named "Shin-Ichiro Kotani"
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Synopsis of recent research by authors named "Shin-Ichiro Kotani"
- Shin-Ichiro Kotani's recent research primarily focuses on understanding and manipulating the behavior of stem and fibroblast cells for potential therapeutic applications in regenerative medicine, particularly related to bladder and bone tissue regeneration.
- One significant finding from his work is the effectiveness of TGF-β inhibitors in ameliorating interstitial cystitis/painful bladder syndrome in animal models, providing insights into the molecular mechanisms behind these treatments.
- Additionally, Kotani has developed innovative methods for the direct conversion of human fibroblasts into functional cell types, such as osteoblasts and urothelial cells, offering promising avenues for cell-based therapies in various biomedical applications.