Publications by authors named "Shin-Ichi Shimanuki"

Article Synopsis
  • Pigs have varying numbers of vertebrae linked to meat production, with wild boars having 19 and commercial breeds 21-23 due to selective breeding.
  • Researchers identified two specific regions (QTL) on chromosomes 1 and 7 associated with an increase in vertebrae, further analyzing a QTL on chromosome 1.
  • The study found that a specific gene (NR6A1) with an amino acid change may influence vertebrae count, indicating its potential role in vertebrae formation in pigs.
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Many quantitative trait loci (QTL) for growth and reproductive traits have been detected on the porcine chromosome region 1qter (SSC1qter), making it one of the most important genomic regions for pig breeding. SSC1q corresponds to human chromosome 9, on which lies transforming growth factor beta receptor 1 (TGFBR1). We cloned the porcine TGFBR1 cDNA and gene (as a candidate for QTL) and analyzed the gene structure and polymorphism.

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We have obtained a partial cDNA and three BAC clones for the porcine insulin-like growth factor binding protein 1 gene (IGFBP-1). Results of fluorescence in situ and radiation hybrid (RH) mapping assigned this gene to porcine chromosome (SSC) 18q24-qter. We found two types of polymerase chain reaction-restriction-fragment-length polymorphisms (PCR-RFLP) in intron 2 by using FokI and AluI.

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