Publications by authors named "Shin-Hyoung Kim"
Article Synopsis
- Adiponectin, produced in fat tissue, boosts fatty acid burning by activating AMPK and affecting key enzymes like ACC and CPT1.
- In an experiment with obese mice on a high-fat diet, researchers observed the impact of BADGE and caffeine over 8 weeks, noting changes in adiponectin levels and enzymes linked to fat metabolism.
- The treatments led to weight loss, reduced fat in the liver, and an early increase in adiponectin and lipid oxidative enzymes, suggesting these changes are tied to the long-term benefits of reducing obesity.
Prp19p is an integral component of the heteromeric protein complex (the NineTeen complex) in the nucleus, and it is essential for the structural integrity of NineTeen complex and its subsequent activation of the spliceosome. We identified Prp19p, which has never been reported in relation to any function outside of the nucleus, as a member of proteins associated with lipid droplets. Down-regulation of Prp19p expression with RNA interference in 3T3-L1 cells repressed lipid droplet formation with the reduction in the level of expression of perilipin and S3-12.
View Article and Find Full Text PDFMatrix Metalloproteinases (MMPs) are crucial enzymes for ultraviolet irradiation-induced photoaging in human skin. Ultraviolet B (UVB) stimulates dermal fibroblasts to increase MMP-1 and -3 expression and extracellular matrix (ECM) degradation in photoaging. We investigated whether phosphatase and tensin homolog (PTEN)/Akt pathway is involved in secretions of MMP-1 and -3 in human dermal fibroblasts.
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