Publications by authors named "Shin-Chia Tsai"
Br J Clin Pharmacol
September 2018
Article Synopsis
- - A nationwide cohort study examined the risk of developing parkinsonism among new users of metoclopramide compared to non-users, revealing that metoclopramide use is associated with a higher risk of this condition, particularly among those with high exposure.
- - Out of nearly 220,000 metoclopramide users, 0.06% developed parkinsonism, which is significantly higher than the 0.03% incidence in matched non-users, with the risk further increasing in individuals on high doses or for long durations.
- - The findings suggest that while the overall risk is low, physicians should exercise caution when prescribing metoclopramide, especially in higher doses or for extended periods, due to
