Morphological and functional characterization of a novel Na+/K+-ATPase-immunoreactive, follicle-like structure on the gill septum of Japanese banded houndshark, Triakis scyllium.

In teleost fishes, it is well-established that the gill serves as an important ionoregulatory organ in addition to its primary function of respiratory gas exchange. In elasmobranch fish, however, the ionoregulatory function of the gills is still poorly understood. Although mitochondria-rich (MR) cells have also been found in elasmobranch fish, these cells are considered to function primarily in acid-base regulation.

Subcellular distribution of urea transporter in the collecting tubule of shark kidney is dependent on environmental salinity.

In the kidney of marine elasmobranchs, urea reabsorption from filtered urine is essential for maintaining high levels of urea in the body. In the kidney of the houndshark, Triakis scyllium, we previously found that a facilitative urea transporter (UT) is localized to a specific nephron segment, the collecting tubule, suggesting that the collecting tubule has an important role in the urea reabsorption process. To elucidate the roles of UT, we transferred T.