Components in SLPE Alleviate AD Model Nematodes by Up-Regulating Gene .

is a perennial herb of the genus in the family Labiatae, which has a wide range of biological activities, mainly including inhibition of acetylcholinesterase, antibacterial, and anti-inflammatory activity. To explore the protective effects and mechanism of action of on Alzheimer's disease (AD), the anti-AD activity of SLE (extracts of ) was determined by using a transgenic () model (CL4176). Analyses included paralysis assay, phenotypic experiments, transcriptome sequencing, RNA interference (RNAi), heat shock assays, and gas chromatography-mass spectrometry (GC-MS).