Publications by authors named "Shimao Zhong"

Article Synopsis
  • * The research identified specific rates of α-thalassemia (17.52%), β-thalassemia (6.92%), and concurrent types (2.32%), along with multiple associated gene mutations and genotypes.
  • * Findings suggest that a significant proportion of couples are at risk of having children with severe forms of thalassemia, highlighting the need for effective genetic counseling and preventive strategies.
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Objective: To analyze the incidence, genotype and hematological feature of hemoglobin H (HbH) disease in West Guangxi region.

Methods: A total of 1246 patients diagnosed with HbH disease from January 2013 to December 2018 in our hospital were enrolled. Red blood cell parameters, hemoglobin electrophoresis, Gap-polymerase china reaction (Gap-PCR) and polymerase chain reaction-reverse dot blot (PCR-RDB) techniques were used to detect the 6 common α-thalassemia mutations and 17 common β-thalassemia mutations.

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Background: Depressive symptoms have been linked with insulin resistance in middle-aged and elderly populations. A strong relationship between peripheral insulin resistance and glucose homeostasis imbalance has been well established in previous studies. The role of serum fructosamine and fasting blood glucose (FBG) in elevating glucose homeostasis has been documented in the literature.

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Objective: To investigate the relationship between atrial fibrillation (AF) and serum soluble CD163.

Methods: A total of 336 patients with heart valve disease were included in this study, including 167 with AF and 169 with sinus rhythm. The clinical data were compared between the two grops, and Logistic regression analysis was used to identify the risk factors associated with AF.

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