Effects of prolonged hydroxychloroquine use on the pancreatic tissue and expected ameliorative effect of lactoferrin in rats (biochemical, histological, and morphometric study).

Hydroxychloroquine (HCQ), an antimalarial drug widely used in treating rheumatoid disorders. Many side effects have been reported with HCQ administration indicating its hazardous effects on various organs. No previous studies reported the effect of long-term administration of oral HCQ on pancreatic tissue.

Assessment of Effects of Rosemary Essential Oil on the Kidney Pathology of Diabetic Adult Male Albino Rats.

Background Diabetic nephropathy is a severe condition that causes persistent kidney problems and chronic renal failure. Rosemary (Rosmarinus officinalis L) is widely recognized for its antioxidant, antidiabetic, anti-inflammatory, antithrombotic, hepatoprotective, and anticancer activities. The current study evaluated rosemary essential oil (REO) effects on biochemical, histological, and immunohistochemical kidney alterations in streptozotocin (STZ)-induced diabetic rats and compared these effects with those of insulin and both combined.

Ameliorating effect of gum arabic on the liver tissues of the uremic rats; A biochemical and histological study.

Background: Gum Arabic (GA) has a protective role against experimental nephrotoxicity and hepatotoxicity. This study explores the possible ameliorating effect of Gum Arabic on the liver tissues of the uremic rats.

Materials & Methods: 50 adult male albino rats were divided into 5 groups; Group I, (negative control).

Amelioration of pulmonary aflatoxicosis by green tea extract: An in vivo study.

Aflatoxins (AFB) are mycotoxins known to be associated with human and animal diseases. The lung is a at risk from AFBexposure either via inhalation or circulation. Green tea consumption is increasing over time due to widespread popularity as antioxidants, anti-inflammatory, and cytoprotective agents.

Could aspartame exacerbate caffeine effects on renal maturation in rat's offspring? A biochemical and histological study.

Background: Caffeine and aspartame (ASP) are mostly used as a diet regimen to reduce overweight. The risk increase if used during critical life periods that may affect the development of fetal organs.

Objective: To evaluate the individual and combined effects of maternal exposure to caffeine and ASP during gestation and lactation on the kidneys' development of rats' offspring.