Publications by authors named "Shima Rezaee"
Article Synopsis
- The study examines how inflammatory processes involving prostaglandins could influence the narrowing of blood vessels (stenosis) in patients with coronary artery issues.
- Researchers focused on measuring specific gene expressions linked to PGE2 metabolism, in addition to assessing the impact of certain microRNAs (miR-520, miR-1297, and miR-34) on these gene expressions.
- Findings showed a significant increase in gene expression and serum levels related to PGE2 metabolism among patients, highlighting the potential role of miR-34 and miR-520 in the synthesis pathway affecting patients with and without stent restenosis.
COX and PTGDS Gene Expression Levels in PGD2 Synthesis Pathway are Correlated with miR-520 in Patients with Vessel Restenosis.
Endocr Metab Immune Disord Drug Targets
September 2021
Background: The vessel restenosis is related to the inflammatory events in subendothelial space. It is proposed that the inflammatory agents affect the prostaglandin synthesis pathway. In this study, we investigated the COX-1, COX-2, PTGDS and miRNA-520a-5p expression levels and the serum 15-Deoxy-Δ-PGJ2 metabolite values in patients with the stenosed and re-stenosed vessels.
View Article and Find Full Text PDFBackground: The integrin family receptors stimulate the cellular proliferation and migration through the focal adhesion pathway by the activation of PTK2, VASP and TSP1 proteins. The purpose of this study was to investigate the integrin-ligated motifs through the activation of focal adhesion pathway.
Methods: A chimeric peptide was predicted from the integrin-mediated ligands by bioinformatics tools.
Mycobacterium bovis is mainly detected in cattle throughout the world. This bacterium is considered the main causative agent of tuberculosis in man and animals. M.
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