Electrical stimulation of prelymbic with different currents intensities on morphine induced spatial memory deficit in rats.

Background: The medial prefrontal cortex (mPFC) is a part of brain reward system involved in cognitive functions such as learning and memory. Previous studies showed that electrical stimulation of prelymbic produced different effects on morphine-induced condition place preference. In this study, we investigated the electrical stimulation with different current intensities on spatial memory in rats.

The effect of medial prefrontal cortex electrical stimulation on passive avoidance memory in healthy and addict rats.

Background: The medial prefrontal cortex (mPFC) is a part of brain reward system involved in cognitive functions such as learning and memory. The mPFC receives strong dopaminergic innervations from ventral tegmental area (VTA) that comprises a portion of the mesolimbic dopaminergic system (MLDS), and sends glutamatergic projections to both the VTA and nucleus accumbens (NAc).

Materials And Methods: In this study, male Wister rats weighing 250-350 g were used.