Comparison of Daily Dose of 400 and 600 Units of Vitamin D in the Prevention of Osteopenia of Prematurity in Infants with a Gestational Age of Less Than and Equal to 32 Weeks.

Background: The use of vitamin D in premature infants is one of the important preventive factors for osteopenia of prematurity, but there are conflicting results on the appropriate doses, so this study aimed to compare the doses of 400 and 600 units of vitamin D in the prevention of osteopenia of prematurity in infants with a gestational age ≤32 weeks.

Methods: This clinical trial study was conducted on 108 premature infants divided into two groups of 54 with a gestational age of ≤32 weeks born between 2020 and 2021 in Shahid Beheshti and Al-Zahrai hospitals in Isfahan. In the first group, daily vitamin D was 400 units from the 7 day of birth, and in the second group, it was 600 units.