Publications by authors named "Shima Gholamalishahi"
Impact of N-Acetylcysteine on Mucus Hypersecretion in the Airways: A Systematic Review.
Int J Chron Obstruct Pulmon Dis
November 2024
Mucus clearance is crucial for airway protection, and its dysfunction leads to chronic obstructive pulmonary disease (COPD) characterized by mucus hypersecretion (MHS) and impaired clearance. MUC5AC and MUC5B mucin proteins are key components of airway mucus, with MUC5AC being particularly responsive to environmental stimuli, making it a potential COPD biomarker. N-acetylcysteine (NAC) is a mucolytic agent with known effects on mucus viscosity and clearance, but its precise mechanisms in COPD remain unclear.
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- The study focuses on ensifentrine, an inhaled drug that inhibits two enzymes (PDE3 and PDE4) and is being researched for its effectiveness in treating chronic obstructive pulmonary disease (COPD).
- Despite encouraging Phase III trial results, there's a need for a detailed review of ensifentrine's therapeutic efficacy, which this systematic review and meta-analysis aims to provide.
- The research intends to show improvements in lung function (measured by FEV) and a decrease in acute exacerbations of COPD, potentially confirming ensifentrine's benefits and guiding future treatment strategies.
Background: Asthma and chronic obstructive pulmonary disease (COPD) are global health challenges leading to substantial morbidity and mortality. While existing guidelines emphasize evidence-based treatments, the potential therapeutic role of thermal water (TW) inhalation remains under-investigated.
Methods: This systematic review followed PRISMA-P guidelines and sought to evaluate the impact of TW in asthma and COPD.
Background: Engaging in physical activity could help improve the quality of life in patients with Alzheimer's disease. The objective of this study was to determine the association between the levels of physical activity and lifestyle, life expectancy, and quality of life in patients with Alzheimer's disease in Iran and Italy.
Methods: A total of 165 participants from Iran and Italy were enrolled in this cross-sectional study.
Status and Trends of Physical Activity Surveillance, Policy, and Research in 164 Countries: Findings From the Global Observatory for Physical Activity-GoPA! 2015 and 2020 Surveys.
J Phys Act Health
February 2023
Background: Physical activity (PA) surveillance, policy, and research efforts need to be periodically appraised to gain insight into national and global capacities for PA promotion. The aim of this paper was to assess the status and trends in PA surveillance, policy, and research in 164 countries.
Methods: We used data from the Global Observatory for Physical Activity (GoPA!) 2015 and 2020 surveys.
Tai Chi and Workplace Wellness for Health Care Workers: A Systematic Review.
Int J Environ Res Public Health
January 2020
Several studies show the positive effects of new non-medical therapies known as complementary and alternative medicines (CAMs). In this context, the discipline of tai chi is obtaining a wider consensus because of its many beneficial effects both on the human body and mind. The aim of this study was to perform a systematic review of the scientific literature concerning the relationship between tai chi practice and wellness of health care workers (HCW) in their professional setting.
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