Publications by authors named "Shilpa Lingaiah"
Article Synopsis
- Gestational diabetes mellitus (GDM) is identified through abnormal results in an oral glucose tolerance test (OGTT), with a lack of clear understanding about how the number of abnormal values relates to negative birth outcomes.
- A study involving 4869 pregnant women in Finland analyzed the connection between the quantity of abnormal OGTT values and adverse perinatal and neonatal results, taking into account various health and social factors.
- Results indicated that women with two or more abnormal OGTT values had significantly higher rates of negative perinatal (35.0% vs. 27.5%) and neonatal outcomes (31.1% vs. 18.9%) compared to those with fewer or no abnormal values.
(1) Hyperglycemia and oral pathology accelerate each other in diabetes. We evaluated whether gestational diabetes mellitus (GDM) is associated with self-reported increased oral health care needs and oral symptoms, including third molar symptoms, during pregnancy. (2) Pregnant women with ( = 1030) and without GDM ( = 935) were recruited in this multicenter Finnish Gestational Diabetes study in 2009-2012.
View Article and Find Full Text PDFObjectives: Altered intestinal permeability and gut barrier dysfunction have been suggested to play a role in the pathogenetic mechanism of polycystic ovary syndrome (PCOS), the most common endocrine and metabolic condition in reproductive-aged women. However, data on intestinal permeability and dysbiosis of the gut microbiota in PCOS is still limited, with conflicting results. To this end, the concentrations of gastrointestinal permeability and gut dysbiosis markers were analysed in women with PCOS.
View Article and Find Full Text PDFObjective: To study the effects of metformin treatment on bone turnover in women with polycystic ovary syndrome (PCOS), as measured by serum concentrations of bone turnover markers.
Design: Post hoc study of a previously conducted prospective multicenter, placebo-controlled, randomized study.
Setting: University clinic.
Objective: Serum levels of retinol-binding protein 4 (RBP4), an adipokine thought to affect systemic insulin sensitivity, were compared between women with polycystic ovary syndrome (PCOS) and non-PCOS controls to evaluate the association of RBP4 with clinical, hormonal and metabolic parameters of PCOS.
Subjects And Methods: Serum RBP4 levels were analysed in 278 women with PCOS (age range 18-57 years) and 191 non-PCOS controls (age 20-53 years) by enzyme-linked immunosorbent assay.
Results: Serum levels of RBP4 were increased in women with PCOS compared with control women in the whole population (45.
Objective: Hyperandrogenism, hyperinsulinaemia and obesity, known characteristics of polycystic ovary syndrome (PCOS), may influence bone mineral density and biochemical markers of bone turnover (BTMs) can provide a noninvasive assessment of bone turnover. To this end, the serum concentrations of BTMs and 25-hydroxyvitamin D (25OHD) were analysed in women with PCOS, and their possible associations with metabolic parameters of PCOS were determined.
Subjects And Methods: Bone formation markers procollagen type I amino-terminal propeptide (PINP) and osteocalcin (OC), and bone resorption marker carboxy-terminal cross-linking telopeptide of type I collagen (CTX), along with 25OHD, were measured in 298 women with PCOS and 194 healthy controls.