Publications by authors named "Shilpa Jasti"
Risk of Adverse Outcomes Associated With Cardiac Sarcoidosis Diagnostic Schemes.
JACC Clin Electrophysiol
August 2023
Article Synopsis
- A study evaluated the association of various cardiac sarcoidosis (CS) diagnostic criteria from different years (1993, 2006, 2014, and 2017) with negative health outcomes in patients.
- Research involved analyzing data from a global cardiac sarcoidosis registry and identified adverse events like mortality and surgeries in 587 patients.
- Results showed patients meeting the 1993 and 2006 criteria had significantly higher chances of experiencing adverse outcomes compared to those who didn't, while the 2014 and 2017 criteria did not show a significant correlation with these events.
Background: Sarcoidosis is an inflammatory disease characterized by the formation of granulomas, which involve the heart in up to 25% of patients. Cardiac sarcoidosis can lead to life threatening arrhythmias and heart failure. While corticosteroids have been used as a treatment for over 50 years, they are associated with hypertension, diabetes, and weight gain, further increasing cardiovascular risk.
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