Wide variation in tibial slopes and trochlear angles in the arthritic knee: a CT evaluation of 4116 pre-operative knees.

Purpose: As surgeons continue to grapple with persistent issues of patient dissatisfaction post-TKA, the literature has focused on the coronal plane when considering alignment strategies but has largely ignored the sagittal and axial planes. The purpose of this retrospective observational cohort study is to evaluate variability in knee anatomy and alignment beyond the coronal plane and rationalise how this relates to existing arthroplasty alignment philosophies.

Methods: 4116 knee CTs from 360 Knee Systems© database of arthritic pre-operative TKA patients were evaluated.

Bioconversion of acrylonitrile using nitrile hydratase activity of sp. APB-6.

sp. APB-6 harboring nitrile hydratase was used in the production of acrylamide from acrylonitrile. sp.