Synopsis of recent research by authors named "Shilong Hu"
- Shilong Hu's recent research focuses on drug discovery and development, particularly in relation to analgesics and anesthetics, with innovative strategies for targeting the delta opioid receptor and the sodium channel Nav1.8 to improve pain management while minimizing side effects.
- His work also explores the engineering of probiotics, specifically Escherichia coli Nissle 1917, for biotechnological applications, including the biosynthesis of therapeutics and industrial metabolites like β-alanine.
- Additionally, Hu has applied novel methods such as deep simulated annealing and molecular transformers to create multifunctional analgesic compounds that can adapt to biological environments, potentially enhancing therapeutic efficacy for complex pain-related disorders.