Physiological characteristics during the formation of aromatic components in xylem of induced by exogenous substances.

An inductive combination of plant growth regulators, inorganic salts, and fungi is essential for the formation of aromatic components in the xylem of . However, the dynamics of xylem physiology and the relationships between physiological properties and aromatic components after artificial induction remain unclear. In this study, the changes in physiological properties of .

Comprehensive study of chiral herbicide flusulfinam uptake, translocation, degradation, and subcellular distribution in rice (Oryza sativa L.).

The biological behavior of flusulfinam, a potential commercial chiral herbicide for rice, has not been well explored. Herein, the uptake of chiral flusulfinam by rice and its transport, degradation, and subcellular distribution in rice (Oryza sativa L.) were investigated.

Aromatic components and endophytic fungi during the formation of agarwood in were induced by exogenous substances.

The process of formation of aromatic components for agarwood in is closely related to endophytic fungi and the result of complex multiple long-term joint interactions with them. However, the interactions between the aromatic components and endophytic fungi remain unclear during the formation of agarwood. In this study, precise mixed solution of hormones, inorganic salts, and fungi was used to induce its formation in , and sample blocks of wood were collected at different times after inoculation.

Novel herbicide flusulfinam: absolute configuration, enantioseparation, enantioselective bioactivity, toxicity and degradation in paddy soils.

Background: Flusulfinam, a novel chiral herbicide, effectively controls Echinochloa crusgalli and Digitaria sanguinalis in paddy fields, indicating significant potential for practical agricultural applications. However, limited information is available on flusulfinam from a chiral perspective. A comprehensive evaluation of the enantiomeric levels of flusulfinam was performed.

Electrospun Fiber Membrane with the Dual Affinity of Chelation and Covalent Interactions for the Efficient Enrichment of Glycoproteins.

As important biomarkers of many diseases, glycoproteins are of great significance to biomedical science. It is essential to develop efficient glycoprotein enrichment platforms and investigate their adsorption mechanism. In this work, a conspicuous enrichment strategy for glycoproteins was developed by using an electrospun fiber membrane wrapped with polydopamine (PDA) and modified with 3-aminophenylboronic acid and nickel ions, named PAN/DA@PDA@APBA/Ni.

Effects of sulfate on the photosynthetic physiology characteristics of under zinc stress.

The effects of sulfate on the zinc (Zn) bioaccumulation characteristics and photophysiological mechanisms of the ornamental plant Hydrocotyle vulgaris were explored using a hydroponic culture under three Zn concentrations (300, 500 and 700mgL-1 ) with (400μmolL-1 ) or without the addition of sulfate. Results showed that: (1) tissue Zn concentrations and total Zn contents increased with increasing hydroponic culture Zn concentrations; and sulfate addition decreased Zn uptake and translocation from roots to shoots; (2) Zn exposure decreased photosynthetic pigment synthesis, while sulfate changed this phenomenon, especially for chlorophyll a under 300mgL-1 Zn treatment; (3) Zn exposure decreased photosynthetic function, while sulfate had positive effects, especially on the photosynthetic rate (Pn ) and stomatal conductance (Gs ); and (4) chlorophyll fluorescence parameters related to light energy capture, transfer and assimilation were generally downregulated under Zn stress, while sulfate had a positive effect on these processes. Furthermore, compared to photosynthetic pigment synthesis and photosynthesis, chlorophyll fluorescence was more responsive, especially under 300mgL-1 Zn treatment with sulfate addition.

Biodegradation characteristics and mechanism of terbuthylazine by the newly isolated Agrobacterium rhizogenes strain AT13.

Terbuthylazine (TBA) is an emerging environmental contaminant that poses moderate to high risk to non-target organisms. In this study, a newly TBA-degrading strain, Agrobacterium rhizogenes AT13, was isolated. This bacterium degraded 98.

Upregulation of LRRC8A by mC modification-mediated mRNA stability suppresses apoptosis and facilitates tumorigenesis in cervical cancer.

Cervical cancer (CC) is one of the most common gynecological malignancies with poor prognosis for advanced CC patients. LRRC8A is a volume-regulated anion channel protein involved in cellular homeostasis, but its role in CC remains largely unknown. In this study, we found that LRRC8A is elevated in CC and associated with poor prognosis.

Fosthiazate exposure induces oxidative stress, nerve damage, and reproductive disorders in nontarget nematodes.

As a forceful nematicide, fosthiazate has been largely applied in the management of root-knot nematodes and other herbivorous nematodes. However, the toxicity of fosthiazate to nontarget nematodes is unclear. To explore the toxicity and the mechanisms of fosthiazate in nontarget nematodes, Caenorhabditis elegans was exposed to 0.

Novel Stereoselective Syntheses of (+)-Streptol and (-)-1-Streptol Starting from Naturally Abundant (-)-Shikimic Acid.

Novel highly stereoselective syntheses of (+)-streptol and (-)-1--streptol starting from naturally abundant (-)-shikimic acid were described in this article. (-)-Shikimic acid was first converted to the common key intermediate by 11 steps in 40% yield. It was then converted to (+)-streptol by three steps in 72% yield, and it was also converted to (-)-1--streptol by one step in 90% yield.

Stereostructure-activity mechanism of cyproconazole by cytochrome P450 in rat liver microsomes: A combined experimental and computational study.

Cyproconazole (CPZ), representing the chiral triazole fungicides, is widely used in the pharmaceutical and agricultural fields. To clarify its potential adverse effects on the generalized CYP-mediated processes within mammalian, a comparative experimental and computational approach was employed to investigate the CYP-mediated metabolism processes of CPZ stereoisomers in rat liver microsomes (RLMs). The depletion rate of CPZ stereoisomers in vitro incubation system with RLMs followed the order RR-> SS-> SR-> RS-CPZ.

Evaluation of exploitive potential for higher bioactivity and lower residue risk enantiomer of chiral fungicide pydiflumetofen.

Background: Pydiflumetofen, as a new succinate dehydrogenase inhibitor (SDHI) chiral fungicide, has been used in crop production because of its broad-spectrum and high-efficiency antifungal activity. However, little is known about pydiflumetofen at the chiral level. The stereoselective bioactivity and degradation of pydiflumetofen enantiomers were therefore investigated.

Enantioseparation and stereoselective dissipation of the novel chiral fungicide pydiflumetofen by ultra-high-performance liquid chromatography tandem mass spectrometry.

Pydiflumetofen is a novel and efficient broad-spectrum chiral fungicide consisting of a pair of enantiomers. A simple and sensitive chiral analytical method was established to determine the enantiomers of this chiral fungicide in food and environmental samples by ultra-high-performance liquid chromatography tandem triple quadrupole mass spectrometry (UHPLC-MS/MS) using QuEChERS method coupled with octadecylsilane-dispersive solid-phase extraction (C-dSPE) as extraction procedure. The specific optical rotation and the absolute configuration of the enantiomers were identified by polarimetry and electronic circular dichroism (ECD).

Efficient and Highly Stereoselective Syntheses of (+)--Quercitol and (-)--Quercitol Starting from the Naturally Abundant (-)-Shikimic Acid.

Efficient and highly stereoselective syntheses of (+)--quercitol and (-)--quercitol starting from the naturally abundant (-)-shikimic acid were described in this article. (-)-Shikimic acid was first converted to the key intermediate by eight steps in 53% yield. It was then converted to (+)--quercitol by three steps in 78% yield and was also converted to (-)--quercitol by five steps in 63% yield.

Novel stereoselective syntheses of -octyl-β-valienamine (NOV) and -octyl-4--β-valienamine (NOEV) from (-)-shikimic acid.

-Octyl-β-valienamine (NOV) 1 and -octyl-4--β-valienamine (NOEV) 2 are potent chemical chaperone drug candidates for the therapy of lysosomal storage disorders. Novel stereoselective syntheses of NOV 1 and NOEV 2 starting from naturally abundant (-)-shikimic acid are described in this article. The common key intermediate compound 5 was first synthesized from readily available (-)-shikimic acid 9 steps in 50% yield.

Activation of β-adrenergic receptor promotes cellular proliferation in human glioblastoma.

Glioblastoma multiforme is the most common and aggressive form of primary malignant brain tumor. Previous evidence demonstrates that β-adrenergic receptors (β-ARs) are closely associated with the occurrence and development of brain tumors. However, the functional role of β-ARs in human glioblastoma and the underlying mechanisms are not fully understood.

[Genetic and prenatal diagnosis for a haemophilia A family with two novel mutations of F8 gene].

Objective: To conduct genetic diagnosis for a family affected with hamophilia A.

Methods: Potential mutations of the F8 gene were analyzed with PCR and Sanger sequencing. Carriers of the mutation were identified through linkage analysis using short tandem repeat (STR) markers.

[Application of array comparative genomic hybridization in prenatal diagnosis of a case with 5q35 deletion syndrome].

Objective: To use combined G-banding and array-comparative genomic hybridization (aCGH) for the prenatal diagnosis of a fetus with 5q35 deletion syndrome.

Methods: Chromosomal karotypes of the fetus and parents were analyzed with G-banding analysis. aCGH was performed to detect minor chromosomal structural abnormalities.

β2-adrenergic receptor activation promotes the proliferation of A549 lung cancer cells via the ERK1/2/CREB pathway.

Lung cancer is one of the most common cancers worldwide and accounts for 28% of all cancer-related deaths. The expression of the β2‑adrenergic receptor (β2‑AR), one of the stress‑inducible receptors, has been reported to be closely correlated with malignant tumors. However, the role of β2‑AR activation in human lung epithelial‑derived cancer A549 cells and the underlying mechanisms are not fully understood.