Publications by authors named "Shile Wu"
Article Synopsis
- Liver transplantation (LT) is often necessary for treating end-stage liver diseases, but it can also lead to serious complications that are not fully understood, particularly regarding immune system dysfunction linked to long noncoding RNAs (lncRNAs).
- This study took a closer look at changes in immune cell types before and after LT, discovering that certain immune cells like CD4 T cells and macrophages experienced significant shifts in their proportions.
- The research identified 12 immunity-related lncRNAs and found that their associated gene networks were enriched in apoptosis-related pathways, suggesting that changes in apoptotic gene expression may influence immune cell dynamics after transplantation.
Increasing evidence shows that the gut fungal mycobiota is implicated in human disease. However, its relationship with chronic helminth infections, which cause immunosuppression and affect over 1 billion people worldwide, remains unexplored. In this study, we investigated the gut mycobiome and its associations with gut homeostasis in a severe helminth disease worldwide: liver echinococcosis.
View Article and Find Full Text PDFObjective: The study aimed to investigate the value of solute carrier organic anion transporter family member 4A1 (SLCO4A1) in thyroid cancer mainly from three aspects: expression, prognosis, and biological function analyses.
Methods: Based on various bioinformatic approaches, genes co-expressed with vascular endothelial growth factor C (VEGFC) in thyroid cancer were used for further survival and expression analyses to identify the target gene. After evaluation of the SLCO4A1 expression levels in thyroid cancer, Cox regression analysis was utilized to predict the risk factors for survival of thyroid cancer patients.
This study examined Echinococcus spp. genotypes and genetic variants isolated from humans as well as domestic and wild animals from the Qinghai-Tibetan Plateau Area using the cox1 gene. All samples except the pika isolates were identified as the Echinococcus granulosus sensu stricto.
View Article and Find Full Text PDFThis study was conducted to investigate the efficacy of a new formulation of MBZ oily suspension (MBZ-OS) in experimentally Echinococcus multilocularis-infected mice. MBZ-OS was prepared and administered to mice infected with E. multilocularis at 12.
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