Publications by authors named "Shikun Wei"

The ferrihydrite-catalyzed heterogeneous photo-Fenton reaction shows great potential for environmental remediation of fluoroquinolone (FQs) antibiotics. The degradation of enoxacin, a model of FQ antibiotics, was studied by a batch experiment and theoretical calculation. The results revealed that the degradation efficiency of enoxacin reached 89.

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Wound infection remains a major challenge for health professionals, because it delays wound healing and increases the overall cost and morbidity. Therefore, the development of new biomaterials with new antibacterial properties and healing effects remains a dire clinical need. To solve this problem, we developed silver nanoparticles embedded in γ-cyclodextrin metal-organic frameworks (Ag@MOF) and platelet-rich plasma (PRP)-loaded hydrogel systems based on methacrylated silk fibroin (SFMA) and methacrylate hyaluronic acid (HAMA) as Ag ion and growth factor delivery vehicles for inhibiting the growth of drug-resistant bacteria and promoting wound healing.

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The high mortality rate of patients with diabetic foot ulcers is urging the appearance of an effective biomedical drug. Senescence is one of the major reasons of aging-induced decline in the diabetic wound. Our previous studies have demonstrated the anti-senescence effect of secretomes derived from human fetal mesenchymal stem cells (hfMSC).

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Objective: To investigate the effect of suture of pronator muscle on forearm function after modified Henry approach for distal radius fractures.

Methods: from January 2018 to December 2020, 220 patients with distal radius fractures were treated with open reduction and locking plate internal fixation through the modified Henry approach. They were divided into two groups according to different suture methods.

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Article Synopsis
  • Diabetic wounds are hard to heal due to infections and issues like low blood flow and long inflammation times, prompting the need for better treatments.
  • Researchers created a hydrogel with oxidized dextran and antimicrobial peptides, mixed with platelet-rich plasma (PRP), which showed significant antibacterial effects and promoted healing in lab tests.
  • In animal studies, the hydrogel notably improved wound healing by reducing inflammation and increasing collagen and blood vessel formation, indicating its potential for treating chronic and infected wounds effectively.
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Skin damaged during sea battles is vulnerable to seawater immersion and bacterial infection. Scaffolds with effective biological function are highly desired for treatment of naval combat wound injuries. Herein, we prepared composite scaffolds of CS/GEL/GMs-CIP.

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