Publications by authors named "Shike Yang"
Article Synopsis
- Osteoarthritis (OA) is a prevalent joint disorder that leads to cartilage breakdown, causing significant pain and potential deformities, with current treatment options showing limitations.
- Cartilage organoids, which mimic natural cartilage structures, can help advance OA research and serve as effective fillers for cartilage repair due to their three-dimensional properties and structure.
- Silk fibroin (SF)-based hydrogels are highlighted as ideal materials for creating these organoids, providing excellent mechanical properties and biocompatibility, and their development is enhanced through artificial intelligence for optimized treatment solutions.
Nanoplastics are prevalent in the environment and emerging evidence suggests they can induce organ injury by activating oxidative stress. Given that both nanoplastics and Zn levels are intertwined with oxidative stress, it is crucial to investigate the influence of nanoplastics on the level of labile Zn and get a better understanding of their cytotoxicity mechanisms. At the organelle level, the Golgi apparatus plays an active role in stress responses.
View Article and Find Full Text PDF