Publications by authors named "Shijun Xia"
Article Synopsis
- The study investigates whether combining linear ablation and ethanol infusion of the vein of Marshall (EIVOM) with pulmonary vein isolation (PVI) improves maintenance of sinus rhythm in patients with persistent atrial fibrillation (AF).
- Conducted as the PROMPT-AF trial across 12 hospitals in China, it enrolled 498 patients, comparing outcomes between PVI alone and the combined approach.
- Primary outcomes focused on the rate of freedom from atrial arrhythmias without antiarrhythmic drugs within a year, with various secondary outcomes related to arrhythmia recurrence and quality of life also assessed.
Background: Early rhythm control reduces the risk of cardiovascular events in patients with atrial fibrillation (AF). Despite the superiority of catheter ablation in maintaining sinus rhythm, the knowledge gaps regarding the prognostic benefits of non-early (onset of AF ≥1 year) ablation remain.
Objective: The study aimed to describe outcomes of non-early AF in the CABANA trial.
Article Synopsis
- - The study aimed to develop reliable methods to predict and prevent atrial fibrillation (AF) by identifying specific plasma proteins associated with the condition, using data from the UK Biobank involving 38,784 participants.
- - Researchers found 21 proteins linked to AF, with COL4A1 and RET showing significant causal relationships; RET is considered a potential drug target.
- - The inclusion of COL4A1 greatly improved the predictive ability of existing AF models, demonstrated by various statistical performance metrics.
Background: The incidence of inflammatory bowel disease (IBD) is increasing every year and is characterized by a prolonged course, frequent relapses, difficulty in curing, and a lack of more efficacious therapeutic biomarkers. The aim of this study was to find key core genes as therapeutic biomarkers for IBD.
Methods: GSE75214 in Gene Expression Omnibus (GEO) was used as the experimental set.
Morphology and location of thrombus and sludge in patients with non-valvular atrial fibrillation.
BMC Cardiovasc Disord
July 2024
Background: Stroke and thromboembolism in nonvalvular atrial fibrillation (NVAF) primarily arise from thrombi or sludge in the left atrial appendage (LAA). Comprehensive insight into the characteristics of these formations is essential for effective risk assessment and management.
Methods: We conducted a single-center retrospective observational of 176 consecutive NVAF patients with confirmed atrial/appendage thrombus or sludge determined by a pre-ablation transesophageal echocardiogram (TEE) from December 2017 to April 2019.
Background: The effect of total intravenous anaesthesia (TIVA) and inhalation anaesthesia (IA) on the prognosis of patients with colorectal cancer after resection is controversial. This study aimed to explore the effects of different anaesthesia methods on the postoperative prognosis of colorectal cancer.
Methods: PubMed, Embase and Cochrane Library databases were searched for relevant literature from each database's inception until 18 November 2023.
Article Synopsis
- The study examines China's hierarchical healthcare delivery system, focusing on how it affects patient behavior in seeking medical treatment and the equitable distribution of health services.
- It involved a survey of over 9,000 patients, analyzing factors like education level, occupation, and medical insurance that influence their choice of healthcare facilities.
- Results showed significant differences in clinical outcomes (like blood pressure and glucose control) based on whether patients chose primary medical institutions or higher-level grade A hospitals.
Background: Depression and anxiety are common mental disorders in patients with colorectal cancer (CRC); however, it remains unclear whether they are related to cancer mortality.
Method: Based on a systematic literature search, 12 eligible studies involving 26,907 patients with CRC were included in this study.
Results: Univariate analysis revealed that anxiety was associated with an all-cause mortality rate of 1.
Evaluation of an algorithm-guided photoplethysmography for atrial fibrillation burden using a smartwatch.
Pacing Clin Electrophysiol
April 2024
Background: Wearable devices based on the PPG algorithm can detect atrial fibrillation (AF) effectively. However, further investigation of its application on long-term, continuous monitoring of AF burden is warranted.
Method: The performance of a smartwatch with continuous photoplethysmography (PPG) and PPG-based algorithms for AF burden estimation was evaluated in a prospective study enrolling AF patients admitted to Beijing Anzhen Hospital for catheter ablation from September to November 2022.
Background: Pudendal nerve block (PNB) is a commonly used anesthesia method that has been widely used in postoperative analgesia for hemorrhoids in recent years. Therefore, we conducted a systematic review and meta-analysis of double-blind randomized controlled trials (RCTs) to analyze the effectiveness of PNB in postoperative analgesia for hemorrhoids.
Methods: Relevant data and studies published from inception until August 14, 2023, were retrieved from PubMed, Embase, and Web of Science to evaluate the beneficial effects of PNB for analgesia following hemorrhoidectomy.
Background: Evidence was lacking for the early choice of radiofrequency ablation (RFA) among patients with early-onset atrial fibrillation (AF).
Hypothesis: This study aimed to explore whether earlier RFA was associated with better clinical outcomes among early-onset AF patients.
Methods: Patients, who were diagnosed with AF before 45 years and underwent their first RFA procedures at baseline of the China Atrial Fibrillation registry, were enrolled and divided into four diagnosis-to-ablation time (DAT) groups: DAT ≤ 1 year, 1 year < DAT ≤ 3 years, 3 years < DAT ≤ 6 years, and DAT > 6 years.
Impact of pre-ablation left appendage flow velocities on long term recurrence of catheter ablation for paroxysmal atrial fibrillation.
Pacing Clin Electrophysiol
November 2023
Background: Despite undergoing a single ablation, many patients with paroxysmal atrial fibrillation (PAF) experience a gradually increasing recurrence rate. This study aims to examine the relationship between left atrial appendage emptying velocity (LAAeV) and filling velocity (LAAfV) profiles and 3-year recurrence of AF after ablation.
Methods: We conducted a prospective study of 658 consecutive PAF patients who underwent their first ablation between January 2018 and December 2019.
Background: Numberous studies have heatedly discussed whether obesity is a risk factor for anastomotic leakage (AL) because of the increasing number of colorectal cancer (CRC) cases and high incidence of CRC in patients with obesity.
Objective: We aimed to explore the relationship between visceral obesity(VO) and AL after CRC surgery. The databases of Pubmed, Embase, and the Cochrane Library were searched for relevant data and articles published until November 1, 2022.
Aims: This study aims to provide representative information on heart failure (HF) patients in China, especially older adults aged ≥75 years. We aim to clarify the age-related discrepancies in performance measures and the modifying effect of age on the impact of HF patients' characteristics on clinical outcomes.
Methods And Results: All HF patients admitted into five tertiary and four secondary hospitals of the Capital Medical University were divided into two groups according to age: 1419 (53.
Background: Anastomotic leakage (AL) is a serious complication of anterior resection for rectal cancer. The use of transanal drainage tubes (TDT) during surgery to prevent AL remains controversial. Therefore, we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to determine the efficacy of TDT in reducing AL.
View Article and Find Full Text PDFBackground: Anastomotic leakage is a serious complication after rectal cancer resection. Intraoperative use of indocyanine green fluorescence angiography (ICGFA) can help prevent anastomotic leakage, but its use is controversial. We conducted a systematic review and meta-analysis to determine the efficacy of ICGFA in reducing anastomotic leakage.
View Article and Find Full Text PDFProximal-type epithelioid sarcoma of the perineum is a rare soft-tissue malignancy, and only 55 cases have been reported in the English literature to date. This tumor has an indetectable early symptom and frequent recurrences. Here, we present the case of a 31-year-old man with proximal-type epithelioid sarcoma of the perineum who underwent wide excision.
View Article and Find Full Text PDFBackground: There is no study analyzing and evaluating the prognostic role of thrombocytosis in Asian patients with colorectal cancer (CRC).
Methods: A systematic search of articles (PubMed, Embase, and the Cochrane Library) was performed to identify studies using the terms Platelet count, Thrombocytosis, Thrombocytoses, Thrombocythemia or Thrombocythemias with colon, colonic, rectal, rectum, colorectal and prognostic, prognosis, survival or outcome.
Results: Thirteen eligible studies with 3964 patients were included.
Objective: We aimed to determine the prevalence of and the factors associated with intraventricular conduction disturbance in the Chinese population.
Methods: Electrocardiographic data from 42,031 people were retrospectively analysed. The weighted prevalences of left bundle branch block (LBBB), right bundle branch block (RBBB), bifascicular block and nonspecific intraventricular conduction delay (NS-IVCD) were calculated.
BACKGROUND Low-density lipoprotein cholesterol (LDL-C) reduction improves cardiovascular outcomes. This study investigates the relationship between lipid levels and outcomes in patients with nonvalvular atrial fibrillation by LDL-C quarters. MATERIAL AND METHODS Patients with atrial fibrillation were enrolled from 31 typical hospitals in China.
View Article and Find Full Text PDFBackground: Health care quality and insurance coverage have improved with economic development in China, but the burden of cardiovascular diseases (CVDs) continues to increase with ongoing gaps in prevention. We aimed to compare the uptake of secondary CVD prevention between stroke and coronary heart disease (CHD) patients in China.
Methods: In a cross-sectional community-based survey of 47,841 adults (age ≥45 years) in 7 regions of China between 2014 and 2016, we identified those with a history of stroke or CHD to quantify disparities in conventional secondary CVD prevention strategies in multivariable logistic regression models.
A simple method is proposed for measuring frequency responses of photodetectors (PDs) based on wavelength-to-time mapping in this paper. The proposed method is an all-optical scheme, which is simple, fast, accurate and free from any extra calibration. Optical pulses emitted from a mode-locked laser are firstly pre-chirped by a spool of dispersive compensation fiber.
View Article and Find Full Text PDFBackground: Atrial fibrillation (AF) is an important risk factor for acute ischemic stroke.
Methods: A nested case-control study was conducted among patients diagnosed with AF, whose information was acquired from the prospective China Atrial Fibrillation Registry (China-AF), from August 2011 to December 2018.
Results: This study compared patients with stroke group (n = 145) with a matched control group (n = 577).