Reversible Microadhesives with Good Adhesion Anisotropy via Dual-Gradient Modulus Constructing.

Bioinspired microadhesives can generate strong adhesion at the interface through van der Waals forces, demonstrating promising potential applications across various fields. However, the inherent conflicts between microstructural stability and compliance, as well as strong adhesion and easy detachment, significantly hinder the development and practical applications of microadhesives. In this work, wedged microadhesives (WMs) of dual-gradient modulus are fabricated via magnetically assisted soft-molding.

Optimizing the zymogram of exogenous proteases in broiler diets by in vitro simulated gastrointestinal digestion and response surface methodology.

Low protein digestibility causes intestinal flora imbalance, wet litter, and nitrogen pollution. The present study aimed to explore the optimal zymogram of exogenous acid protease (ACP), neutral protease (NEP), alkaline protease (ALP), and keratinase (KEA) in corn-soybean based diets for broilers. The hydrolysis performances of the four monocomponent proteases were presented by enzymatic hydrolysate gross energy (EHGE) and improved dry matter digestibility (IDMD), which were tested via the in vitro simulated digestion method.

The burden of ischemic stroke in Eastern Europe from 1990 to 2021.

Background And Purpose: Ischemic stroke is a significant public health concern, particularly in Eastern Europe, where the burden remains high. This study aims to evaluate the trends and burden of ischemic stroke in Eastern Europe from 1990 to 2021, providing insights into epidemiological changes and informing public health strategies.

Methods: We used data from the Global Burden of Disease 2021 database to comprehensively assess regional and national ischemic stroke indicators in Eastern Europe.

Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features.

Background: The capability of mNGS in diagnosing suspected LRTIs and characterizing the respiratory microbiome in lung cancer patients requires further evaluation.

Methods: This study evaluated mNGS diagnostic performance and utilized background microbial sequences to characterize LRT microbiome in these patients. GSVA was used to analyze the potential functions of identified genera.

Influence of tension cracks on moisture infiltration in loess slopes under high-intensity rainfall conditions.

Loess slopes with steep gradients are particularly prone to vertical tension cracks at the crest, resulting from unloading and other factors. These cracks significantly affect the spatiotemporal distribution of moisture infiltration during rainfall, potentially leading to slope instability. This study investigates the impact of crest-tension cracks on moisture infiltration in loess slopes under extreme rainfall conditions, focusing on crack position, depth, and width.

All-Inorganic Lead-Free Cs₂AgBiBr₆/ZnO Artificial Retina Synapse Based on Photoelectric Synergistic Dual-Mechanism for Neuromorphic Computing.

Adaptive learning capability of optoelectronic synaptic hardware holds promising application prospects in next generation artificial intelligence, and the development of biometric retina perception is sternly hampered by three crucial issues, including well-balance between excitatory and inhibitory, non-volatile multi-state storage, and optimal energy consumption. In this work, a novel CsAgBiBr/ZnO non-volatile optoelectronic synapse is proposed and successfully programmed with optical excitatory and electronic inhibitory in the light of dual-mechanism: Lead-free perovskite CsAgBiBr guarantees abundant photogenerated carrier concentration, and the process of carrier capture and release occurs in ZnO layer, which can collaboratively modulate various synaptic plasticity behaviors depending on distinct stimulus. Consequently, multi-bit storage is attained with the dual-mechanism non-volatile memory (DNVM) as a function of consecutive light spikes.

Bibliometric Analysis of Probiotic Bacillus in Food Science: Evolution of Research Trends and Systematic Evaluation.

With the in-depth and comprehensive research on probiotic Bacillus, it has become a hot topic in food science. However, the current status of research using bibliometric analysis to assess the application of probiotic Bacillus in food science has not been comprehensively reviewed. The Web of Science (WOS) database was used in this review's bibliometric analysis to determine the hotspots for research as well as the extent of completed experiments.

Housing temperature influences exercise-induced glucose regulation and expression of exerkines in mice.

The impact of housing temperature on exercise-induced metabolic adaptations is not well understood, despite extensive research on the benefits of exercise for metabolic health. The aim of this study was to elucidate how housing temperatures influence the molecular responses and metabolic benefits of exercise in mice. Male C57BL/6N mice were housed at either room temperature (RT, 21°C) or in a thermoneutral environment (TN, 29°C) and subjected to either a 6-week or acute exercise regimen.

Molecular Insights into Binary Ionic Melts of Protic Ionic Liquid 1,2,4-Triazolium Methanesulfonate and Methanesulfonic Acid Electrolytes.

Binary ionic melts formed by a protic ionic liquid (PIL) 1,2,4-triazolium methanesulfonate ([TAZ][MS]) dissolved in methanesulfonic acid are studied as non-stoichiometric electrolytes. The composition-driven structure-property relationship of methanesulfonic acid is explored at varying molar fraction ratios from 0/100 to 10/90, 20/80, and 30/70 by the addition of 1,2,4-triazolium methanesulfonate [TAZ][MS] IL. To unveil molecular characteristics of these mixtures of [TAZ][MS] PIL and CHSOH, we performed classical molecular dynamics simulations at varying temperatures from 293 to 303, 363, and 423 K.

Effects of higher-order interactions and impulsive vaccination for rumor propagation.

This paper introduces a rumor propagation model with saturation incidence, based on hypergraph theory. Hypergraphs can capture the higher-order interactions between nodes in a social network, where the node degree is substituted with hyperdegree. First, the threshold for rumor spreading model is obtained, the global asymptotically stable of the rumor-free equilibrium, and the global attractive and global asymptotically stable of the rumor-prevailing equilibrium are proved.

Triglyceride glucose index: a significant prognostic marker of heart failure in patients with chronic kidney disease.

Background: Triglycerides and glucose (TyG) index, a relatively convenient method for assessing insulin resistance, has been confirmed as an independent predictor both for chronic kidney disease (CKD) and cardiovascular disease (CVD) in previous studies. However, a few studies focus on the prognostic value of TyG index for CVD in patients diagnosed with CKD, especially in advanced CKD patients. In this study, we aim to investigate the prognostic value of TyG index for heart failure (HF) in patients with non-dialysis CKD stage 3-5.

Rapid screening and identification strategy of lactic acid bacteria and yeasts based on Ramanomes technology and its application in fermented food.

There is an urgent need for quick, sensitive, thorough, and low-cost preliminary screening and rapid identification method for probiotic resource development. Here, we constructed a culture-free, accurate and sensitive "separation-enrichment-detection" rapid evaluation and identification method of probiotics in fermented food based on Ramanomes technology, and established a Ramanome reference of lactic acid bacteria and yeasts by AgNPs nanostructure array (AgNPs NSA) chips with uniform "hot spots" and high signal enhancement ability as SERS substrates. Systematic cluster analysis could clearly distinguish among different genera of lactic acid bacteria and yeast, and could indicate the affinity and difference between lactic acid bacteria of the same genus and yeast of the same genus.

Absolute testing of optical flats using minimum norm least squares solutions.

A laser Fizeau interferometer measures surface form by comparing the wavefronts reflected from a reference surface and the surface under test. The measurement accuracy is limited by the unknown absolute form error of the reference flat. Absolute testing offers a strategy to break through the limitation.

Modular Assembly of Heterotrifunctional Molecules Enabled by Iodosulfonylation of Allenes and Subsequent Amination.

Beyond the rapid achievements of therapeutic heterobifunctional molecules, some recent efforts have focused on constructing heterotrifunctional molecules, aiming at developing more potent and selective therapeutic agents or emerging additional functions to heterobifunctional molecules. However, the synthesis of these complex molecules requires a specific design and lengthy steps. We have developed a two-step strategy for the modular construction of heterotrifunctional molecules, enabled by the sustainable and convenient iodosulfonylation of allenes followed by S2'-selective amination.

Study on the lower limit of gas detection based on the snapshot infrared multispectral imaging system.

Snapshot multispectral imaging system is extensively utilized in the petrochemical industry for gas monitoring due to its intuitive imaging, traceability, and ability to monitor a wide range of gases. Determining the detection capability of the different bands of the multispectral camera for the gases to be monitored is a crucial prerequisite for the operationalization of the camera. The current evaluation methods of detection capability are mainly for single-spectrum cameras, which require constructing complex experimental environments and have poor applicability to different gases.

Isolation and purification of lactic acid bacteria and yeasts based on a multi-channel magnetic flow device and rapid qualitative and quantitative detection.

Rapid isolation and identification of lactic acid bacteria and yeasts during fermentation is of great significance for quality control and regulation of fermented foods. In this study, we prepared a multi-channel magnetic flow device for rapid separation and purification of lactic acid bacteria and yeast, and based on SERS spectrum, we made rapid qualitative and quantitative analysis of Lactobacillus plantarum, Lactococcus lactis and Saccharomyces cerevisiae. The results showed that the synthesized Synthesized FeO-Van antibiotic magnetic beads are paramagnetic; FeO-Van antibiotic magnetic beads achieved capture efficiencies of more than 98.

Research on Defect Detection Method of Fusion Reactor Vacuum Chamber Based on Photometric Stereo Vision.

This paper addresses image enhancement and 3D reconstruction techniques for dim scenes inside the vacuum chamber of a nuclear fusion reactor. First, an improved multi-scale Retinex low-light image enhancement algorithm with adaptive weights is designed. It can recover image detail information that is not visible in low-light environments, maintaining image clarity and contrast for easy observation.

Acid-Stable Cu Cluster Precatalysts Enable High Energy and Carbon Efficiency in CO Electroreduction.

The electrochemical reduction of CO in acidic media offers the advantage of high carbon utilization, but achieving high selectivity to C products at a low overpotential remains a challenge. We identified the chemical instability of oxide-derived Cu catalysts as a reason that advances in neutral/alkaline electrolysis do not translate to acidic conditions. In acid, Cu ions leach from Cu oxides, leading to the deactivation of the C-active sites of Cu nanoparticles.

Scaling CO Electrolyzer Cell Area from Bench to Pilot.

To contribute meaningfully to carbon dioxide (CO) emissions reduction, CO electrolyzer technology will need to scale immensely. Bench-scale electrolyzers are the norm, with active areas <5 cm. However, cell areas on the order of 100s or 1000s of cm will be required for industrial deployment.

Enhanced Second-Harmonic Generation in Thin-Film Lithium Niobate Circular Bragg Nanocavity.

Second-order nonlinearity gives rise to many distinctive physical phenomena, e.g., second-harmonic generation, which play an important role in fundamental science and various applications.

Ring Transformation of Cyclopropenes to Benzo-Fused Five-Membered Oxa- and Aza-Heterocycles via a Formal [4+1] Cyclization.

In the context of the growing importance of heterocyclic compounds across various disciplines, numerous strategies for their construction have emerged. Exploiting the distinctive properties of cyclopropenes, this study introduces an innovative approach for the synthesis of benzo-fused five-membered oxa- and aza-heterocycles through a formal [4+1] cyclization and subsequent acid-catalyzed intramolecular O- to N- rearrangement. These transformations exhibit mild reaction conditions and a wide substrate scope.