Publications by authors named "Shihua Fang"

Article Synopsis
  • CAR-T therapy frequently results in neurotoxicity, which varies significantly in clinical presentation.
  • A study analyzed data from the FDA Adverse Event Reporting System between January 2017 and March 2023, focusing on neurological side effects related to CAR-T products.
  • Among the findings, 18.17% of reports involved neurological events, with tisagenlecleucel leading in severe outcomes, while unique adverse signals were identified for different CAR-T therapies.
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Purposes: To explore the value of metagenomic next-generation sequencing (mNGS) in diagnosing pneumocystis jiroveciipneumonia (PJP) in the immunocompromised patients.

Methods: Data of 122 patients with PJP in an immunosuppressed state and 67 non-PJP patients were collected. The diagnostic efficacy of mNGS was compared with the conventional methods, including Gomori methenamine silver (GMS) staining and serum (1,3)-β-D-glucan (BDG).

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Objective: To analyze the associations between menopause and hypertension/isolated systolic hypertension (ISH) among rural females in Hanzhong, Shaanxi Province, China.

Methods: In this cross-sectional study, 3030 residents were selected by stratified random sampling and investigated by questionnaire survey and physical examinations. Data of the females were analyzed to explore the impact of menopause on blood pressure by quantile regression and to investigate the associations between menopause and hypertension, ISH, and isolated distolic hypertension (IDH) by logistic regression.

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